Scientist II/Sr. Scientist, In Vivo Pharmacology

Boston, MA
Research /
Full Time /
On-site
Here at Kelonia Therapeutics, we aren’t just a preclinical company; we’re trailblazers in viral engineering, pushing the boundaries of in vivo lentiviral gene and cell therapy. We're not just a team; we're dreamers on a mission to bring the promise of cell and gene therapy to every patient in need.

At Kelonia, we've gathered a group of pioneers in cell and gene therapy to lead our journey, with extraordinary scientific founders at the helm, providing the cutting-edge technology that sets us apart. We're not just building a company; we're cultivating a culture—one that values both skill and care.

Are you ready to be a part of our remarkable journey? We are looking for someone exceptional to join our growing team as a Scientist in the In Vivo Pharmacology group. This isn't just a job; it's an opportunity to contribute to groundbreaking therapies, to be part of a company's inception, and to make a transformative impact on patients' lives. If you're passionate about scaling a company from the ground up, making a real difference, and shaping the inclusive culture we're proud of, this opportunity is tailor-made for you. Join us and be a driving force in achieving excellence in viral engineering.

What You’ll Do:

    • Lead in vivo murine model development and characterization for various programs.
    • Design, plan, conduct, document, analyze and interpret preclinical in vivo studies in support of various programs.
    • Work collaboratively to plan, execute, and analyze ex vivo characterization of multiple parameters such as bio-distribution and transduction efficiency.
    • Prepare and present data and interpretations to cross-functional stakeholders.
    • Help draft technical reports that document in vivo studies.
    • Mentor and guide junior colleagues.

What You’ll Bring:

    • Strong scientific expertise in Pharmacology or related discipline, PhD, and non-PhD candidates encouraged to apply (level based on experience)
    • In-depth experience in animal handling and drug administration including i.v./i.p./s.c. dosing, in-study blood sampling, IVIS imaging, necropsy, tissue harvest and processing.
    • Understands and implements study protocols in accordance with regulatory requirements for compliance with IACUC guidelines.
    • Demonstrated initiative in experimental design, troubleshooting, and performing robust data analysis.
    • Excellent organizational and documentation skills.
    • Adaptable analytical person with a get-it-done attitude.
    • Experience with humanized mouse models, engineered human T cells, and secondary ex vivo assays (eg. multicolor flow cytometry, PCR, MSD, IHC, ISH) is a plus.
    • Ability to work collaboratively, meet deadlines, and prioritize and flexibly balance multiple workstreams.
Our goal at Kelonia is to promote a healthy work/life balance and we hope the benefits we provide are a direct reflection of that goal. We offer a hybrid workplace that provides employees with flexibility to work in the office or remotely dependent on job responsibilities. *We also offer a team-focused environment with a top-notch benefits package (health, dental, flexible PTO, and commuter) to match. Kelonia fosters a collaborative and inclusive workplace that allows you to become a part of a small team that places equal value on talent development and meeting company goals. 

Kelonia Therapeutics is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Kelonia does not accept unsolicited resumes from any source other than directly from candidates.