Research Biostatistician

San Francisco or Remote /
Biostatistics /
About Unlearn

Recent progress in artificial intelligence coupled with a growing resource of longitudinal patient data from historical clinical trials and real world sources provides an unprecedented opportunity to transform clinical trials and speed the development of new medicines.  

Unlearn is a science-first company that has invented the first machine learning platform for creating Digital Twins of patients in clinical trials — comprehensive simulations that answer “what would likely happen to this patient if he/she were randomized to the control group?”.

Using information from Digital Twins to estimate treatment effects with PROCOVA™ reduces required sample sizes, increases statistical power, and provides patient-level treatment response information. 

It’s about increasing confidence in trial results. 

It’s about bringing new medicines to patients faster.

It's about time.

Your role at Unlearn

As a Research Biostatistician, your primary responsibilities are:

Develop new methods for utilizing Digital Twins in clinical trial design
   Characterize and mathematically prove benefits of current methodology
  Extend current methodology to new endpoints and trial designs
   Publish and present new methods at statistical and clinical conferences
  Conduct simulations to check sensitivity of methods to assumptions

Advise regulatory team
   Stay abreast of latest regulatory guidances related to estimating treatment effects
   Support statistical sections of regulatory submissions

Collaborate with the Unlearn Data Science team and applied biostatisticians
   Identify the qualities of Digital Twins that are most essential for clinical trial usage
   Assist applied biostatisticians in explaining methods to customers
   Conduct simulations to check sensitivity of methods to assumptions


    • PhD in Biostatistics or equivalent experience with an advanced degree in a similar field
    • Experience with randomized controlled trial study design
    • Ability to develop and publish mathematical proofs
    • Ability to run simulation studies in python or R
    • Excellent communication skills
Compensation & benefits

Unlearn offers compensation commensurate with experience as well as a competitive benefits package, including:

Generous equity participation
Unlimited PTO plus company holidays
Annual company-wide shutdown between Christmas and New Years holidays
Professional development budget to attend conferences or other events
401k plan with generous matching
Company-subsidized medical, dental, & vision insurance plans
Commuter benefits plan
Paid Parental Leave

Unlearn is not currently offering visa sponsorships for any position. Please only apply if authorized to work in the U.S.

Unlearn is an equal opportunity employer. We embrace diversity and create an inclusive work environment because inclusion and diversity are essential to achieving our mission to create AI to simulate biology and improve patients' lives.

Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.

All employees who work at Unlearn must comply with our COVID-19 vaccination requirement or receive an approved exemption.