Medical Director, Clinical Neurology

United States /
Clinical Development /
/ Remote
At Alector, our mission is to develop therapies that empower the immune system to combat neurodegeneration and cancer. Our team is solely focused on developing treatments for some of the most challenging diseases facing our society. We are supported in this mission by experienced and accomplished scientists and clinicians, leading healthcare investors, and pharma company partners who share in our commitment to bettering the lives of patients.

The Medical Director will support one or more development programs involving drug candidates in Alzheimer’s Disease, Frontotemporal Dementia, and other neurodegenerative diseases. The focus will be on crafting and executing clinical trials in early clinical development and working as a medical monitor for one or more studies.

Activities include responsibility for advancing priority clinical programs through study design and execution, development of biomarker strategies, as well as interpretation of data from clinical studies. You will interact with multiple levels of management within Alector, key external partners in the medical and scientific community as well as with global regulatory authorities. 

During your first year, your goals will include:

    • Provide leadership for programs that integrate the individual’s extensive knowledge in basic and clinical science, neurology disease areas with knowledge from the medical community around the world.
    • Integrate the scientific rationale, regulatory and payor requirements, input and advice from medical and patient advocacy groups, product development plan, and commercial goals to build a solid strategic framework for the Clinical Development Plan (CDP).
    • Act as Sponsor Medical Monitor with oversight of clinical trial activities and patients safety on behalf of the Clinical Science Group at Alector.
    • Establish aggressive clinical development timelines, incorporating key decision points and Go/No Go criteria for each CDP.
    • Develop and maintain relationships with program counterparts in Commercial, Research, Regulatory, Biomarkers, Clinical Operations, and Statistics.
    • Establish external collaborative relationships to augment Alector’s capabilities in support of the clinical development programs.
    • Participate in clinical reviews of the safety of Alector programs.
    • Contribute to the development of critical initiatives and specified Business Development activities. 

We would love to hear from you if you have:

    • Minimum two (2) years of experience in clinical research
    • Proven experience in clinical development preferred, but not strictly required
    • Deep understanding of basic science related to neurodegeneration and immunology
    • Capacity and willingness to work effectively across disease areas.
    • Demonstrated leadership and team-building skills as well as being able to perform effectively in a dynamic environment.
    • Demonstrated strategic and critical thinking.
    • Excellent communication and organizational skills.
    • The ability to lead directly and by influence, including strong problem solving, conflict resolution, and analytical skills. 


    • MD, MD / PhD or DO credentials. Neurology training with subspecialization degenerative CNS disorders preferred.

Alector is a phenomenal place to learn and grow. Alector is a dynamic environment where teams are encouraged to experiment, take ownership of decisions, and question convention to solve complex problems. At Alector, we value shared wins, perseverance, and a growth mindset.

Alector was named on Fortune’s "Best Workplaces in Biopharma" top list for small and medium-sized companies for the second year! And we moved up from #16 to #11 in 2022.

Among the things you'll discover at Alector on Day 1 and throughout your tenure: Committed and driven colleagues, a bold and important company goal, brand-new brightly lit offices in Oyster Point, right at the heart of Biotech Bay. Alector offers flexible remote work options, and competitive compensation and benefits. Come join us!

Base salary ranges from $50,000 to $300,000 and will be determined by the candidate's level, qualifications, skill set, and experience.

At Alector, we believe that hard-working teams include people from a wide variety of backgrounds and experiences who can challenge each other’s assumptions with fresh perspectives and bring creative ideas to the table. We are committed to building an open, diverse, and inclusive environment for all employees. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, sexual orientation, age, marital status, veteran status, or disability status, or any other characteristics protected under applicable federal, state, or local laws.

Employees of Alector working on-site are required to be vaccinated against COVID-19, and are required to provide proof of vaccination. Employees may be entitled to an exception or reasonable accommodation if they cannot be vaccinated because of a disability/medical necessity, or sincerely held religious belief. 

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, perform essential job functions, and receive other benefits and privileges of employment. Please contact us to request accommodation.