Research Associate - Temporary
South San Francisco, CA
Antibody Discovery and Protein Engineering /
Temporary /
On-site
We are seeking a research associate in the ADPE group (12-month contract). The candidate is expected to support the Protein Sciences team in providing high-quality biologics in a timely manner for biochemical, biophysical, and biological characterizations to drive the advancement of novel therapeutics. The candidate will be responsible for the purification, QC of all biologic molecules ( including bispecific and multi-specific antibodies, fusion proteins) and will support developability studies. Tasks will include analytics of proteins by analytical SEC, SDS-PAGE, DSF, DLS, endotoxin assessment, etc. Purification strategies will include the use of AKTA systems and various chromatography techniques (protein-A/G, Ni-NTA, SEC, IEX, HIC, etc).
Responsibilities:
- Responsible for purification of high-quality monoclonal antibodies, bi-specific/multi-specific antibodies, fusion proteins, as well as reagent proteins from CHO cells and HEK293 cells
- Early molecular assessment for antibody developability evaluation
- Document and present experimental results at team meetings
Qualifications:
- B.S. with 0-2 years of industry experience
- Self-motivated and highly collaborative with excellent oral and written communication skills and organization skills
- Strong desire to drive technical innovation
- Experience with protein purification and a wide range of biochemical/biophysical and analytical methods, such as SDS-PAGE, HPLC/UHPLC, DSF, DLS, endotoxin quantitation/removal
- Ability to thrive in a fast-paced environment in a creative, open, collaborative, team-oriented setting
$25 - $35 an hour
Hourly rate ranges will be determined by the candidate’s level, qualifications, skill set, and experience.
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