Scientist Nonclinical Sciences

South San Francisco, CA
Nonclinical Sciences /
Full-time /
Our mission is to develop therapies that empower the immune system to combat neurodegeneration and our team is focused on developing treatments for some of the most challenging diseases facing our society. We are supported in this mission by experienced and accomplished scientists and clinicians, a novel portfolio of programs, leading healthcare investors, and pharma company partners, who share in our commitment to bettering the lives of patients and realizing a world where we make brain disorders history 

As a Scientist for the Nonclinical Sciences team focusing on bioassay development, you’ll work closely with scientists in Research, Development, Clinical and Regulatory teams to advance our drug discovery programs. You will be able to contribute across a variety of programs ranging from early research to clinical stage and have broad involvement in work central to Alector’s strategic goals. You will apply your existing technical skills, learn new skills, and play a key role in the nonclinical and clinical development of the programs and help grow the company. 

During the first year, your goals will include:

    • Develop and qualify pharmacokinetic (PK), pharmacodynamic (PD), immunogenicity (ADA), and non-cell based and cell-based neutralizing antibody assays for various programs and perform PK, PD, and ADA sample analysis supporting Toxicology, Research and Clinical studies.
    • Summarize bioanalytical results, prepare, and review technical reports in support of business development activities and regulatory filings.
    • Participate in regular cross-functional team meetings and present as needed.

We'd love to hear from you if you have:

    • A BSc or MSc in Biology, Pharmacology, Immunology, or a related science degree with minimum of 3-5 years of industry experience ideally in ligand binding assay development, cell culture and cell-based assays.
    • Experience in developing and/or validating pharmacokinetics, biomarkers, immunogenicity assays for biologics, and non-cell based and cell-based assays for the detection of neutralizing antibodies to drug products.
    • Detailed understanding of the FDA’s and EMA’s regulatory guidance related to bioanalytical assays.
    • Excellent communication and writing skills and thrive in an environment where we work independently and on teams.
    • Proven a track record of learning new skills and troubleshooting independently and take pride in being self-motivate and efficient.
$130,000 - $146,000 a year
Base salary ranges will be determined by the candidate’s level, qualifications, skill set, and experience 

At Alector, our vision is bold, people are our priority, and our values are at the core of everything we do. Our dynamic and flexible environment encourages our teams to experiment, take ownership of decisions, and question convention to solve complex problems. We value shared wins, perseverance, and a growth mindset, which drives us forward, together.  

Among the things you'll discover at Alector from your very first day are our committed and driven colleagues, a bold company vision, and new, modern offices designed to inspire innovation and collaboration in South San Francisco, right at the heart of Biotech Bay. Our benefits are thoughtfully designed around Alectorians and their loved ones and include flexible hybrid work options, competitive compensation, and comprehensive and unique benefits that enhance your health and well-being. Come join us! 
We believe that hard-working teams include people from a wide variety of backgrounds and experiences who can challenge each other’s assumptions with fresh perspectives and bring creative ideas to the table. We are committed to building an open, diverse, and inclusive environment for all employees. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, sexual orientation, age, marital status, veteran status, or disability status, or any other characteristics protected under applicable federal, state, or local laws.  

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, perform essential job functions, and receive other benefits and privileges of employment. Please contact us to request accommodation. 

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