Director, Clinical Supply Operations
Remote
Technical Operations – Supply Operations /
Full time /
Remote
Alpine Immune Sciences is a leading clinical-stage biopharmaceutical company dedicated to discovering and developing innovative, protein-based immunotherapies for autoimmune and inflammatory diseases. Exciting challenges lie ahead—guided by our core values, we’ll meet these challenges. Join us!
We are seeking a highly experienced and motivated individual to join our team as the Clinical Supply Chain Director. In this role, you will be responsible for overseeing all aspects of clinical supply chain management to ensure the timely and efficient delivery of investigational drugs for our clinical trials including but not limited to planning, master scheduling, inventory management, sourcing, logistics, warehousing, and distribution. You will collaborate closely with cross-functional teams including Clinical Operations, Regulatory Affairs, Quality Assurance, Manufacturing, and external vendors to develop and execute comprehensive supply chain strategies.
Duties and responsibilities:
• Develop and implement end-to-end clinical supply chain strategies to support the successful execution of clinical trials, from study start-up to close-out.
• Manage and optimize inventory levels of investigational drugs across multiple clinical trials, accounting for study requirements, patient enrollment projections, and site demand forecasts.
• Work closely with internal and external stakeholders to optimize inventory ensuring adequate drug supply for ongoing and upcoming studies.
• Oversee packaging, labeling, and distribution activities for investigational drugs, ensuring compliance with quality and regulatory requirements and industry standards.
• Establish strong relationships with contract manufacturing organizations (CMOs), packaging and labeling vendors, and third-party logistics providers to ensure reliable and cost-effective supply chain solutions.
• Monitor and mitigate supply chain risks, such as manufacturing delays, regulatory changes, and distribution challenges, to minimize impact on clinical trial timelines.
• Drive continuous improvement initiatives to enhance the efficiency, flexibility, and scalability of the clinical supply chain operation.
• Provide leadership and mentorship to the clinical supply chain team, fostering a culture of collaboration, innovation, and excellence.
Qualifications:
• Bachelor's degree in supply chain management, logistics, pharmacy, or related field; advanced degree (e.g., MBA, MS) preferred.
• Minimum of 8-10 years of experience in clinical supply chain management within the pharmaceutical or biotechnology industry, with a proven track record of successfully managing complex clinical trials.
• In-depth knowledge of clinical trial drug supply management principles, GMP/GCP regulations, and industry best practices.
• Strong analytical skills with the ability to interpret data, forecast demand, and optimize inventory levels effectively.
• Excellent communication and interpersonal skills, with the ability to collaborate effectively with cross-functional teams and external partners.
• Proven leadership experience, with the ability to inspire and motivate team members to achieve departmental goals and objectives.
• Demonstrated ability to thrive in a fast-paced, dynamic environment and adapt to changing priorities and deadlines.
• Strong project management skills with the ability to manage multiple priorities simultaneously and drive projects to successful completion.
• Experience and expertise with global clinical supply chain, including US, Europe, Asia, and Oceana.
• Demonstrated experience managing CMOs and CROs. Cold chain distribution experience highly desired.
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At Alpine we engage equitable workplace strategies to ensure fair compensation. Actual compensation is dependent upon current market data, experience, and pay parity within our organization. This is a Director level position with a compensation range of $190,000 to $225,000. Note that there is a strong preference for candidates to be located in one of the following five states: CA, MA, NC, OR, or WA. We take care of our employees with a competitive benefits package that includes stock options, annual bonus, premium medical, dental, and vision coverage for employees and their dependents, as well as life and disability benefits, FSA, and 401(k) plans. We believe quality time outside the office is vital to our employees’ satisfaction at work, so our flexible PTO plan of 160 hours, generous holiday time (generally 12 days), and parental benefits encourages team members to take time off so they can come back refreshed. Alpine team members enjoy competitive salaries and equity participation (stock options).
Alpinists share a passion for meaningful work and are committed to solving the most complex problems in immunology to create new therapies for patients. We believe in innovative thinking, collaboration, flexibility, bias for action, and healthy debate. To foster our team of outstanding scientists and business professionals, we provide a premier work environment with a state-of-the-art lab and office spaces with truly inspiring views, and an open design to facilitate teamwork.
Our treasured culture has been shaped by our diverse team who truly enjoys working and playing together. We nurture Alpine’s culture in many ways, including all-company social events and happy hours, lunch-and-learn and education opportunities, interest groups like book club and movie nights, peer-to-peer recognition programs, a robust wellness program to help support physical, mental, and emotional health, and more.
Alpine is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status. Alpine is also committed to compliance with all fair employment practices regarding citizenship and immigration status.
Our office and lab are located in the blossoming biotech neighborhood of Eastlake in Seattle. Alpinists enjoy the flexibility to work onsite, remotely, or a hybrid schedule, with evolving options as we prioritize keeping Alpinists safe and healthy. Onsite employees enjoy an open-office layout with comfortable huddle rooms and Zoom Room-enabled conference rooms, a spacious breakroom and kitchen with a coffee bar and snacks, and rooftop access to enjoy gorgeous views of Lake Union and Gas Works Park.
Exciting challenges lie ahead—guided by our core values, we’ll meet these challenges. Join us!
