Medicinal Chemist
Paris
Portfolio /
Full-time (French "CDI") /
Hybrid
About AQEMIA
AQEMIA is a next-gen pharmatech company generating one of the world's fastest-growing drug discovery pipeline.
Our mission is to design fast innovative drug candidates for dozens of critical diseases, such as immuno-oncology.
Our unique approach leverages quantum-inspired physics algorithms to power generative AI in designing novel drug candidates—without relying on experimental data.
We already delivered several drug discovery successes within our internal pipeline and through collaborations with pharmaceutical companies. Our most advanced programs are currently in vivo optimization.
As a Medicinal Chemist you will work at the interface of chemistry and biology, designing and optimizing compounds that drive our projects from hit generation through to preclinical candidates. If you’re excited to leverage your scientific expertise to help build the future of therapeutics, we’d love to hear from you!
Your Mission
- Of primary importance at AQEMIA : closely collaborate with our technological platform, including atomistic calculations and generative AI, with the goals of (i) challenging and improving the platform, and (ii) designing innovative molecules
- Optimize lead compounds and transform them into drug candidates, pragmatically applying our technology
- Autonomously execute, and interpret complex activities to identify pharmaceutical candidates
- Prepare and follow tasks given to our CROs to support drug discovery projects, including the synthesis of novel small molecules and the generation of biological data
- Follow and drive one or several programs simultaneously in medicinal chemistry
- Contribute to patent filings
- Maintain clear, accurate, written records of decisions and progresses
- Collaborate with our project managers to establish clear projections in terms of timelines and costs
Your Qualifications
- PhD in synthetic or organic chemistry, academic post-doc is a plus
- 10 years of experience in industrial drug discovery with similar role
- Strong track record in organic synthesis and compound design for drug discovery
- Strong interest in AI-driven and computer-assisted drug design
- Proven ability to work with interdisciplinary teams and effectively communicate complex data
- Familiarity with molecular modeling, SAR analysis, and ADME optimization
- Excellent problem-solving skills and a track record of scientific innovation
- Ability to thrive in a fast-paced, collaborative environment
- Autonomous, curious, creative, strong analytical skills. Can explain complex topics with simple words.
Why Join Us ?
At AQEMIA, we work for a mission: joining us means having your own impact on changing the way drugs are discovered, and helping to shape the direction of our fast-growing company and team.
Expanding Drug Discovery Pipeline : Focused on critical diseases several types of cancers, with in vivo proof of concept/patent stage programs. Collaborations with top Pharma, including a $140M Sanofi deal.
Interdisciplinary Team : brilliant talent from tech and life sciences.
Experienced Leadership : Founders with 15+ years at ENS, Oxford, Cambridge, and BCG.
DeepTech Recognition: Part of French Tech 120 and France 2030.
Prime Location : Based in central Paris with the possibility of 2 remote days per week.
International Environment : The work language is English - relocation support and French lessons granted if needed.
Strong Financial Backing : $60M raised from leading European deeptech investors
