Scientist/Sr. Scientist, Analytical Development

Boston, MA /
Analytical Development /
/ On-site
Company Background
Catamaran Bio is developing novel, off-the-shelf CAR-NK cell therapies designed to treat a broad range of cancers, including solid tumors. Our proprietary capabilities enable us to harness the natural cancer-fighting properties of NK cells and enhance and tailor their effectiveness with the power of synthetic biology and innovative non-viral cell engineering. We are using our TAILWIND™ Platform, an integrated suite of technologies, to specifically address the end-to-end methods of engineering, processing and manufacturing NK cells and rapidly advance our pipeline of CAR-NK cell therapy programs.

Catamaran is seeking a diligent, motivated, and collaborative Scientist/Senior Scientist in Analytical Development to help advance our Immune Cell Therapies to the clinic. This position is focused on cell therapy product characterization and will play a key role in the design and execution of assays designed to support process development and regulatory filings. The ideal candidate is excited to develop new medicines for cancer, driven to learn, technically competent, and has significant experience with cell and molecular biology techniques and principles, especially involving cell-based assays in 96 well plate format. The strong desire to learn and positive collaborative attitude are more important than experience in any specific method. 


·       Understanding of CMC and regulatory requirements for analytical method development, qualification and control strategy for Cell/Gene therapy or Biologics products
·       Develop, perform, and report on analytical assays, such as flow cytometry, IncuCyte, MSD/Luminex, plate-based cytotoxicity, qPCR/ddPCR, and nucleic acid preparation
·       Work in close collaboration with platform teams, as well as Contract Research and Manufacturing Organizations
·       Present results to the team and company, as well as author and review batch records, technical reports, and supporting methods
·       Mentor junior scientists in the execution of experiments
·       Meticulously maintain records and documents for IP and regulatory filings

Education, Experience and Qualifications:
·       Ph.D. or MD/Ph.D., in relevant scientific discipline with 3-5 years of directly related experience or equivalent; Master’s degree or native equivalent with 8+ years of relevant experience; or Bachelor’s degree with 10+ years of experience.
·       Previous experience in gene/cell therapy and cell engineering, especially with exposure to Analytical Development/CMC/QC activity is preferred
·       Facility with software including MS Office applications, FlowJo, JMP, GraphPad Prism
·       Ability to work independently, multitask, and meet deadlines in a rapidly changing environment, all with a pro-active and team-oriented positive attitude
·       Excellent organization and communication skills
Catamaran Bio is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.