Senior Scientist, Process Development HTE

Boston, MA
Research and Technical Operations – Technical Development /
Full Time /
On-site
Company Overview

Cerevel Therapeutics is dedicated to unraveling the mysteries of the brain to treat neuroscience diseases. We are tackling neuroscience diseases with a differentiated approach that combines expertise in neurocircuitry with a focus on receptor selectivity. Our portfolio of pre-commercial neuroscience assets targets a broad range of central nervous system (CNS) disorders, including schizophrenia, epilepsy, Parkinson’s disease and substance use disorder.  
 
Headquartered in the Greater Boston area, we are bold thinkers, deep experts, resilient pathfinders, and transparent partners who push the boundaries of scientific understanding to unlock breakthrough CNS therapies that have real impact on people’s lives.
 
Cerevel aspires to develop and nurture a culture characterized by trust, respect, courage, curiosity, and compassion, with a relentless focus on mission and results.  Our patient-centricity guides our purpose, how we treat each other and what we work on every day.  The successful candidate will bring their own unique thinking and approach to Cerevel while sharing our core values and convictions.

Role Summary

Cerevel Therapeutics is seeking a talented synthetic organic chemist or engineer for a role in Process Development as a Senior Scientist, Process Development HTE.  The Senior Scientist will apply and grow their expertise in small molecule drug substance process development as they contribute to Cerevel’s pursuit of its rich small molecule pipeline spanning pre-clinical through commercial candidates.  This is a tremendous opportunity to apply and grow your skills in process development activities from the discovery chemistry interface (form selection and toxicology batch production) to preparation for commercial launch activities.  Aided by and establishing leveraging Cerevel’s internal laboratory capabilities while managing external partners, the Sr. Scientist will develop scalable, cost-efficient, environmentally-sound synthetic processes for Cerevel’s novel candidates.  This is an opportunity to be a part of a well-funded, growing, and collaborative company with a shared goal of realizing Cerevel’s mission of delivering innovative therapies for CNS disorders like Parkinson’s, Alzheimer’s, and epilepsy. 

Key Responsibilities

    • Conducting hands on activities for process development and optimization work in the lab to support small molecule drug substance for all phases of development
    • Conducting crystallization and physical/chemical property characterization of intermediates and drug substances
    • Hands on experiences on high throughput experimentation
    • Leading and contributing to scientific and technical discussions to support Cerevel pipeline
    • Authoring and process reports and transferring technical reports to external vendors
    • Partner with other functions such as analytical, drug product development and manufacturing, clinical supply, quality assurance, regulatory and external CMO to deliver on programs

Required Qualifications

    • Proven track record applying fundamental principle of chemical engineering to support internal and external development activities
    • Ability to prioritize and manage numerous activities simultaneously
    • Hands on experience on synthetic process development, optimization and scale up
    • Capable of working in a laboratory environment with chemical reagents
    • Excellent written and verbal communication skill 

Desired Qualifications

    • Experiences with drug substance development and manufacturing
    • Experiences with CMO management and project management

Education

    • PhD in Organic Chemistry or chemical engineer with a minimum of 3 years’ relevant industrial experience
Cerevel is an Equal Opportunity Employer and does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, non-disqualifying physical or mental disability, national origin, veteran status or any other characteristic protected by applicable law