Sr Scientist II, Protein Sciences

Bethlehem, PA /
OraSure Technologies – Product Office - R&D /
/ On-site
The OraSure family of companies empowers the global community to improve health and wellness by providing access to accurate, essential information. Our ability to positively affect change is powered by the innovative tools, services and diagnostics we deliver to the market. 

Together with its wholly owned subsidiaries, DNA Genotek, Diversigen, and Novosanis, the OraSure family of companies provides its customers with end-to-end solutions that encompass tools, services, and diagnostics. Our 800+ colleagues play a role in empowering people to discover healthier lives by creating effortless tests, collection kits, and services. 

It’s first-to-market, innovative products include rapid tests for the detection of antibodies to HIV and Hepatitis C (HCV) on the OraQuick® platform; sample self-collection and stabilization products for molecular applications; and oral fluid laboratory tests for detecting various drugs of abuse.  

Here at the OraSure family of companies our innovative sampling tools, services and diagnostics unlock access to accurate, essential information that advances global health and well-being. Our products include molecular sampling kits for the genome and microbiome, cutting-edge services and analytics, rapid diagnostics for infectious disease, and tests for substance abuse.  

The Sr Scientist, Protein Sciences, is a key researcher and future team leader of critical initiatives in particular on protein and antibody expression, purification, and molecular cloning. Responsibilities include analyzing research and development projects, planning and execution at the bench. Strong cell culture and protein biochemistry skills will be used in this role.  Scope of work may include laboratory and field research, product development, and technical support.  This role is responsible for the research and development of new and novel antigens and antibodies for use in the medical diagnostic industry using the latest and most advanced technologies. In this role, you will be enabling in house capabilities through industry standard practices for bacterial and mammalian expression systems. 

We invite you to read through the below and submit your application to us. A member of our team will review it, and if you are selected you will be contacted for interview. Due to the volume of applications we receive, we are not always able to respond to those not selected for interview as quickly as we would like. If you do not hear from us regarding this role, but see other opportunities in the future you are interested in applying for, we will welcome your application then too. 

Snapshot of Responsibilities

    • Spending majority of time (70%+) as a bench scientist, you will be:
    • Responsible for teamwork on multiple protein engineering projects through Research and to Product Development to support new products.
    • Applying your extensive experience to troubleshoot laboratory issues, using both equipment and appropriate methods.
    • Providing technical advice on competitor products, new products, and scientific concepts that may lead to new products.  Maintaining an ongoing surveillance of marketing, scientific, and patent literature to stay abreast of new developments and products that may impact OraSure’s business
    • Participating in the preparation of supporting data documents for regulatory submission to the FDA in support of our regulatory department.
    • Designing experiments, evaluates data, communicates results to others and determines subsequent course of action consistent with project and company goals.
    • Working as an independent team member with low level of supervision and direction from management. You may be responsible for associates’ contribution and timeline for specific projects. 
    • Preparing and presenting papers at scientific meetings and/or publishing papers in scientific journals.
    • You may have direct reports and responsible for reviewing, coaching, developing critical skills
    • You may lead technology transfer and supports validation of new products & processes.
    • You may participate in cross-functional core teams as required
    • You will maintains timely execution of notebook and documentation according to Quality Department
    • Be responsible for supplies ordering, equipment maintenance and cleaning lab.

What You Bring

    • Experienced in technical skills for expression and purification of recombinant proteins: Affinity, SEC, HIC, IEX, analytical and preparative chromatography.
    • Demonstrated technical and scientific skill and experience in designing recombinant proteins, framework analysis for antibodies, designing vectors for prokaryotic and mammalian expression systems.
    • Experienced in plate-based assays, development of reagents and optimization of samples and strategies.
    • Experienced in BLS2+ lab, working with potentially infectious human samples, performs all work under safety guidelines at all times
    • Experience with infectious diseases such as bacterial and viral pathogens and samples.
    • Demonstrable communication skills, written and oral, including a high level of proficiency with Microsoft Word, Excel, and PowerPoint, alignment software, MolBio software/tools.
    • Conjugation expertise, Immunoassay experience, affinity measurements by SPR/BLI, epitope mapping/design a plus.
    • Willing to work at the bench and to assist in teaching technical skills to subordinates and/or colleagues.
    • Must be able to demonstrate scientific knowledge and application.
    • Excellent analytical and problem-solving skills.
    • Excellent time-management skills, multi-tasking skills and efficient execution on deliverables.
    • Excellent communication skills, both written and in presentation. Ability to be collaborative at all levels and cross-functionally, accept direction when needed, enthusiastic, self-motivated required
    • Capable of working in a laboratory or office environment 40 hours/week
    • Able to frequently stand, walk and bend to have the ability to access various areas of the laboratory
    • Capable of operating a computer 
    • Capable of giving and following instructions
Don’t meet every single requirement? 
Studies have shown that women and people of colour are less likely to apply to jobs unless they meet every single qualification in the job posting. We are committed to creating a diverse and inclusive environment, so we strongly encourage you to apply even if you don't believe you meet every single qualification outlined. 
The OraSure family of companies encourages applications from all qualified candidates who represent the full diversity of the communities in which we operate. This includes, but is not limited to people with disabilities, candidates from Indigenous communities, candidates from the Black, LGBTQ2S+, or racialized communities.   
What we offer:  
- Tiered Medical PPO, EPO, Vision and Dental coverage  
- Disability and Life Insurance Benefits  
- Generous 401K plan and company-matching contributions  
- Highly competitive paid time-off  
- Maternity Leave and Parental Leave Coverage  
- Employee Referral Program – you may be eligible for a cash bonus if your referrals are hired   
- Employee Assistance Program 
- Employee Service Recognition  
- Job-related Training Programs 
- Ability to participate in Teams, Committees, Events and Clubs 
- Depending on the role you may be eligible to work in a hybrid environment or fully remotely  
- Free Onsite Parking 

Culture, People & Community 

The OraSure family of companies recognizes that the long-term health of our business is directly connected to the health of the planet, local communities and the OraSure family of companies employees.  

- LIVE IT Committee – committed to creating an environment that embodies our values  
- Diversity, Equity & Inclusion Council hosts various events across all company locations such as monthly book club and mentorship program 
- Wellness Committee empowers colleagues to make critical decisions to improve and protect health 
- Sustainability Committee aims to minimize impact on the environment 
- Social Committee who organize and run events for both remote and onsite employees, to create connection and community 

At the OraSure family of companies, we have a clear vision; cultivate an environment of equal employment opportunity where we do not tolerate discrimination or allow the harassment of employees or applicants on the basis of sex, gender identity, sexual orientation, race, color, religious creed, national origin, physical or mental disability, protected Veteran status, or any other characteristic protected by law with regard to any employment practices.  

The OraSure family of companies aims to create and foster workplaces that reflects and contributes to the global communities in which we do business and the customers and partners we serve. This includes all communities impacted by our corporate presence. As part of this commitment, the OraSure family of companies and its subsidiaries will ensure employees and applicants are provided reasonable accommodation per request.  If you require disability-related accommodation during the recruitment process, please contact Lauren Wildfang at The OraSure family of companies will consult with all applicants who request disability-related accommodation during the recruitment process to ensure that the accommodation provided takes into account the applicant's individual accessibility needs.