Mouse Technician/Research Associate, In vivo Pharmacology

Massachusetts
Research
Full-time

About Dragonfly
Founded in 2015 by Dr. Tyler Jacks, head of the Koch Institute at MIT, Dr. David Raulet, one of the world's leading experts in Natural Killer (NK) cell biology, and Bill Haney, a longtime tech entrepreneur and investor, Dragonfly Therapeutics develops novel first-in-class therapeutics targeted at Natural Killer cells and other cells of the innate immune system. Our therapies are designed to counterbalance immune suppressive factors present in the tumor microenvironment and mobilize anti-cancer immune responses, and are expected to be potent as single agents as well as in treatment combinations with existing cancer immunotherapies – such as T cell treatments.  Dragonfly’s Scientific Advisory Board and founders are major figures in cancer biology and immunology, and launched Dragonfly to harness the power of the immune system to provide breakthrough cancer treatments for patients.

Mouse Technician/Research Associate, In vivo Pharmacology
Dragonfly Therapeutics seeks a motivated and skilled Technician/Research Associate to support new cancer drug development. The successful candidate will work with Dragonfly’s team to discover and develop novel therapies that stimulate immune responses against solid and hematologic cancers.
 
Responsibilities
- In vivo mouse studies: injections (i.v., i.p., etc.), subcutaneous tumor inoculation and growth monitoring, necropsy
- Tissue processing (organs, spleens, lymph nodes) and single cell preparation
- Maintenance of cancer cell lines and development of cell line derivatives
- Flow cytometry based phenotyping of immune and cancer cells
- Execute SOPs, generate new assays and troubleshoot when needed
- Generate, analyze, interpret, organize, and present experimental data
- Manage daily work flow independently and seek advice when appropriate
- Work collaboratively within the Dragonfly team

Qualifications
- B.S. or M.S. degree in biology, immunology, or relevant field
- 2+ years of relevant research experience, industry experience is a plus
- Must have expertise in handling mice and experience with various dosing routes, tissue collection and bleeds
- Experience with the development of pharmacology studies
- Flow cytometry and experience with primary cell culture (preferably of T or NK cells) are a plus
- Knowledge of basic cell biology, molecular biology, and biochemistry techniques
- Proficiency with data analysis methods and software
- Strong organizational and record-keeping skills, and written and verbal communication skills
- Ability to multi-task with a high attention to detail
- Ability to work in concert with a team as well as independently
- Self-motivated, conscientious, and enthusiastic about curing cancer