Research Associate - Cell Biology
South San Francisco, CA /
R&D – Cell Biology /
Full Time
GenEdit is a rapidly-growing, early-stage company that is developing a proprietary and novel delivery platform with the potential to transform genetic medicine. Our interdisciplinary team works together across chemistry, payload, formulation, screening, and preclinical groups to develop the next generation of gene therapies. GenEdit fosters an exciting and dynamic environment where we value impactful data and creative solutions to accelerate our progression from a platform technology to a pipeline of therapeutic candidates. We are seeking talented and motivated individuals to join our team and are expanding across all functions within the organization. Join us in South San Francisco, CA, to be at the forefront of the future of gene therapy.
GenEdit’s Cell Biology team is seeking a highly self-motivated and goal-oriented biologist with experience in cell-based assays using mammalian primary cells and cell lines. The position will be responsible for characterizing GenEdit’s novel polymer nanoparticles across a wide array of cell types to deliver genetic medicines, including mRNA, siRNA, pDNA, and Cas9 RNP. The successful candidate will have experience handling multiple types of mammalian cell cultures, for example HEK293, iPSC, and neurons, and will have experience performing various microplate-based assays, such as viability/toxicity, fluorescence, luminescence, and automated microscopy. Characterization of payload activity will include nucleic acid extraction, PCR, RT-qPCR, and immunoassays such as ELISA and Western Blot. This position will work cooperatively with multidisciplinary teams, keep detailed and organized lab records, and present results at team meetings.
This is a unique opportunity to work at the intersection of genomics and therapeutics and participate in the development of a transformative technology. The successful candidate will be a highly organized, collaborative, resourceful, and effective team-player with enthusiasm to tackle challenging scientific and technical problems.
Job title and salary will be determined by relevant experience.
Desired Skill Sets
- Experience with cell culture of various cell lines and primary cells – iPSC, NPCs and neurons a plus
- Experience with molecular biology techniques such as PCR, RT-qPCR, DNA sequence analysis, ELISA, Western Blot
- Experience with microplate cell-based assays, immunocytochemistry, and quantitative microscopy
- Ability to execute on standard operating procedures with accuracy and precision
- Excellent written and oral communications skills
- Excellent organization and use of network drives and infrastructure
- Experience with Prism, Python, or matlab, for automated data analysis and visualization a plus
- Experience with gene therapy and/or nanoparticle technology is a plus
- >1yr experience at a biotech or pharma company
Qualification Requirements
- Bachelor’s or Master’s degree emphasized in cell biology, biotechnology, or related field
- 2-4 years wet lab research experience in biology
- >1 year experience in mammalian cell culture techniques
- US work authorization required
At GenEdit we are always looking to hire the absolute best talent and recognize that diversity in our experiences and backgrounds is what makes us stronger. We hire candidates of any race, color, ancestry, religion, sex, national origin, sexual orientation, gender identity, age, marital or family status, disability, veteran status, and any other status. These differences are what enable us to work towards the future we envision for ourselves, and the world.
