Senior Scientist, NGS

Boston, MA /
Foundry: NGS /
Full-time
Our mission is to make biology easier to engineer. Ginkgo is constructing, editing, and redesigning the living world in order to answer the globe’s growing challenges in health, energy, food, materials, and more. Our bioengineers make use of an in-house automated foundry for designing and building new organisms. Today, our foundry is developing over 40 different organisms to make different products across multiple industries.

Core to our organism engineering pipeline is the testing and analysis of our engineered strains. We leverage 2nd and 3rd generation sequencing as well as other ‘omics to get a detailed picture of the performance of our strains. To help facilitate this, we’re looking for a dedicated Senior Scientist to join our NGS Team. Critical to this role is a strong background in diverse applications of NGS, as well as expertise in molecular biology across a range of input materials and species.  We'll look to you to help design experimental plans, make process improvements, and guide the future development of our NGS capabilities.

Responsibilities

    • Design and perform NGS wet lab experiments, using a wide range of bacterial, fungal, plant, and mammalian cells across multiple NGS platforms
    • Develop innovative sequencing and molecular biology assays
    • Miniaturize and automate high-throughput laboratory processes
    • Develop and implement DNA and RNA extraction methods for a variety of challenging starting materials
    • Develop, validate, and onboard new technologies for NGS and sample preparation
    • Collaborate with computational team members on experimental design and analysis to optimize new analytic approaches using NGS technologies
    • Liaise with program teams to ensure NGS and data analysis are optimally incorporated in the project plans at an early stage, to avoid duplication of effort
    • Effectively communicate scientific results to technical and non-technical audiences

Desired Experience and Capabilities

    • PhD with at least 5 years of experience (or MS with at least 8 years of experience) in a relevant field of biological sciences
    • Managerial experience within a relevant field (i.e., molecular web lab operators)
    • Clinical laboratory experience a plus
    • Familiarity with Jupyter notebooks
    • Familiarity with high-throughput automation
    • Experience with at least some of the following techniques and platforms:  RNAseq, RT-qPCR, ChIPseq, 10X genomics, Illumina NGS, Oxford Nanopore, PacBio
    • Expertise with a variety of sequencing applications, such as transcriptomics, resequencing, de novo genome assembly, metagenomics, epigenetics, etc.
    • Ability to work effectively in a cross-functional team environment
    • Flexibility and willingness to learn in a rapidly changing, growing organization


To learn more about Ginkgo, check out some recent press:
Ginkgo Bioworks CEO on scaling up Covid-19 testing: ‘If we try, we can win’ (CNBC)
Ginkgo raises $70 million to ramp up COVID-19 testing for employers, universities (Boston Globe)
Ginkgo Bioworks Redirects Its Biotech Platform to Coronavirus (Wall Street Journal)
Ginkgo Bioworks Provides Support on Process Optimization to Moderna for COVID-19 Response (PRNewswire)
The Life Factory: Synthetic Organisms From This $1.4 Billion Startup Will Revolutionize Manufacturing (Forbes)
Synthetic Bio Pioneer Ginkgo Raises $290 Million in New Funding (Bloomberg)
Ginkgo Bioworks raises $350 million fund for biotech spinouts (Reuters)
Can This Company Convince You to Love GMOs? (The Atlantic)

We also feel that it’s important to point out the obvious here – there’s a serious lack of diversity in our industry, and that needs to change. Our goal is to help drive that change. Ginkgo is deeply committed to diversity, equality, and inclusion in all of its practices, especially when it comes to growing our team. Our culture promotes inclusion and embraces how rewarding it is to work with people from all walks of life.  

We’re developing a powerful biological engineering platform, so we must remain mindful of the many ways our technology can – and will – impact people around the world. We care about how our platform is used, and having a diverse team to build it gives us the best chance that it’s something we’ll be proud of as it continues to grow. Therefore, it’s critical that we incorporate the diverse voices and visions of all those who play a role in the future of biology.

It is the policy of Ginkgo Bioworks to provide equal employment opportunities to all employees and employment applicants.