Test Engineer / Analytical Chemist

Boston, MA
Foundry: Test
Full-time

Ginkgo is building an industrialized foundry for organism engineering. Our first foundry, Bioworks1, launched in Spring 2015. We designed Bioworks1 to be a single foundry capable of delivering many organisms to customers in many markets. Already, we're using Bioworks1 to concurrently develop 10+ organisms across multiple species and products.

Core to our organism engineering pipeline is the testing and analysis of our engineered strains. We leverage NGS and mass spectrometry to get a detailed picture of the performance of our strains. Our analytical approaches are designed to work across dozens of different cultured ingredients and scale 100-1000X via software and automation. We are seeking analytical chemists to improve and scale our existing technologies in Biowork1 and define and develop the next set of analytical technologies that will lie at the center of Bioworks2.

The ideal candidate has led the development of a high-throughput assay from development, validation through to successful operation at scale, most likely for NGS or mass spec based assays. A demonstrated ability to evolve a process in response to changing technology and demands is essential. Experience in a mixed team of software developers, process engineers, and biologists is important.

Responsibilities

    • Operate and improve processes for strain analysis in Bioworks1
    • Apply DOE approaches to refine and improve sample extraction and assay methods
    • Translate assays to be performed by software + automation
    • Work hand in hand with software and automation engineers to scale up sample extraction methods and assays 100-1000X
    • Develop processes for verification and quality control of assays to ensure low CV and reproducibility
    • Collaborate with software engineers to ensure that all generated data is captured, stored and analyzed in Ginkgo's LIMS

Requirements

    • BS or MS in chemistry, bioengineering, chemical engineering or equivalent
    • Experience with analytical methods like LC-MS, HPLC, GC-MS or NGS
    • Familiarity with software or laboratory automation a plus
    • Previous experience in microbial metabolomics
    • Previous experience in proteomics

To learn more about Ginkgo, check out some recent press:

http://www.wired.com/2015/11/move-over-jony-ivebiologists-are-the-next-rock-star-designers/

http://fortune.com/2015/07/23/ginkgo-bioworks/

https://medium.com/the-os-fund/a-new-era-of-industrial-engineering-using-biology-dd4571aa6d27


We also feel it’s important to point out the obvious here – there’s a serious lack of diversity in our industry and it needs to change. Our goal is to help drive that change. We hope to continue to build a company whose culture promotes inclusion and embraces how rewarding it is to work with engineers from all walks of life. Making biology easier to engineer is a tough nut to crack - we can’t afford to leave any talent untapped.

It is the policy of Ginkgo Bioworks to provide equal employment opportunities to all employees and employment applicants.