Research Associate, Biology
Cambridge, MA /
Glympse Bio is pioneering the development of synthetic biomarkers – biochemical sensors developed using breakthroughs in science, engineering, medicine and artificial intelligence – that are engineered to be tunable to a range of diseases and offer earlier measures of response to disease and treatment. Our breakthrough technology measures protein activity from a blood draw to revolutionize disease diagnosis and monitoring. We are building a novel biomarker technology platform from the ground up, laying the foundation for innovative diagnostics which combines nanotechnology with AI to improve the lives of potentially millions of patients worldwide.
We are a vibrant and dedicated team working at the forefront of scientific discovery and clinical development. We are agile, resilient, and creative problem solvers. We are committed to bringing the best products to patients and at Glympse you will have the opportunity to work alongside a high functioning, interdisciplinary and collaborative team to develop an entirely new diagnostic modality.
We are seeking a motivated Research Associate to join our growing research organization and contribute to the development of novel diagnostics for liver cancer, with the goal of predicting patients with early- and late-stage cancers eligible to upcoming treatments and monitoring drug response. This position will involve the close coordination of efforts with scientists in biology, biochemistry, and biocomputational, as well as participation in experimental design and execution, data generation, and analysis. The candidate will be responsible for communication of findings to the research team and active participation in project teams. The position will afford the opportunity to work alongside a highly dynamic and collaborative team to develop an entirely new diagnostic modality.
- Support target identification and validation efforts to advance liver HCC biology sensed by our diagnostic.
- Assist with development of pre-clinical liver HCC models to identify new targets and characterize contribution of HCC protease to liver cancer progression.
- Work closely with CROs and pharmaceutical partners to identify protease targets in biofluids from HCC patients.
- Design, develop and execute ELISA-based assays and IHC staining to verify target identification.
- Execute, troubleshoot, and optimize standard protocols, and survey scientific literature to inform the development of additional assays.
- Write and implement IACUC mouse protocols to allow pre-clinical work for the liver HCC project.
- Rigorously document research methods and results in an electronic lab notebook, and effectively communicate findings to the organization at internal meetings.
- BS or MS in biology, biochemistry, bioengineering, molecular biology or similar discipline with 2+ years of relevant laboratory research experience
- Experience with ELISA-based assays, IHC staining, qPCR and Western blotting techniques
- Support the experiments designed by the lead Scientist using in vivo studies in mice which requires animal handling, blood sampling and organ harvest is a plus
- Passionate about scientific discovery, self-motivated, and eager to learn new skills and contribute to the success of the organization
- Exceptional organizational, communication, and critical thinking skills, and the ability to thrive in an interdependent and idea-rich environment
- Capability to design and execute thoughtful experiments, troubleshoot, and implement innovative solutions
The Ideal Candidate
· Brings courage, character, humility, and energy to work every day
· Is motivated to improve the lives of the people they serve
· Is excited about what might be possible, sees problems as challenges to be overcome, and is driven by curiosity and creativity
· Is optimistic and committed to Glympse’s mission
We are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to age, color, creed, disability, gender identity, national origin, protected veteran status, race, religion, sex, sexual orientation, and any other status protected by applicable local, state, or federal law.