Clinical Laboratory Supervisor, 3rd Shift 10:00pm - 8:30am, Sun-Wed #3555

Durham, NC
Research & Development – Lab Operations /
Full-Time /
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in Menlo Park, California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.

For more information, please visit

GRAIL is seeking a Clinical Laboratory Supervisor for the Clinical Laboratory. The Clinical Laboratory Supervisor is responsible for the general supervision of Clinical Laboratory personnel and the daily operations of the Analytical Laboratory. The Clinical Laboratory General Supervisor may also perform high complexity laboratory testing on patient specimens, interpret and report patient results, and perform quality control and quality assurance procedures while complying with all applicable local, state, and federal laboratory requirements. This is an onsite role requiring 4 days a week in Durham, NC. This full time position involves working in our lab between the hours of 10:00 PM to 8:30 AM (overnight), Sunday through Wednesday.


    • Lead, manage and develop a team of Technical Personnel
    • Supervise Technical Personnel and reporting of findings
    • Conduct performance evaluations and provide ongoing coaching and support
    • Perform testing requiring special scientific skills
    • Monitor and ensure acceptable performance specifications are maintained, including: review of quality control, scheduled instrument and equipment maintenance, other quality assurance activities as assigned
    • Ensuring test system performance by: initiating preventive and/or remedial actions when test procedures deviate from the laboratory’s established performance specifications, in the event of non-conformances, ensuring test results are not reported until corrective action has been taken and the test is performing according to laboratory established performance specifications
    • Verify personnel are trained and deemed proficient prior to performing testing on patient specimens independently.
    • Ensure staff have competency assessments as needed.
    • Ensure action is taken when personnel do not perform as expected on competency assessments.
    • In the absence of the director, responsible for the proper performance of all laboratory procedures.
    • Be responsible for the daily operations of the laboratory including but not limited to scheduling, independently troubleshooting and resolving technical and non-technical high complexity problems.
    • Manage the testing and validation of new laboratory equipment and procedures.
    • Perform laboratory tests, procedures, and analyses according to the laboratory's standard operating procedures as needed.
    • Review, interpret, and report patient results as needed.
    • Perform, review and oversee reagent qualifications.
    • Perform, review and document laboratory quality control procedures, as needed.
    • Operate, maintain, and troubleshoot laboratory equipment, as needed.
    • Effectively communicate technical information to technical and non-technical audiences.
    • Maintain stringent standards for quality, identifying any issues which might adversely impact the quality of test results and/or employee safety, and communicating these to the appropriate management representatives as necessary for resolution.
    • Report all concerns of test quality and/or safety to the Manager or Safety Officer.
    • Conduct competency assessments of laboratory personnel.
    • Initiate, plan, execute, and close projects related to process improvement and new technology implementations.
    • Utilize Lean, Six Sigma, or other process improvement methodologies to enhance laboratory processes.
    • Maintaining records that demonstrate that proficiency testing samples are tested in the same manner as patient specimens.
    • Perform laboratory, administrative, and other duties as assigned

Preferred Qualifications:

    • MS / BS in molecular biology or related with 4 + years of Clinical Laboratory Medical Technologist Experience. (4 years of clinical laboratory medical technologist experience with a Master’s degree or 6 years of clinical laboratory medical technologist experience with a Bachelor's degree)
    • Working knowledge of local, state and federal laboratory regulations.
    • At least 2 years of supervisory experience
    • Outstanding professionalism, leadership, communication and organizational skills
    • Strong communicator with ability to maintain open communication with internal employees, managers and customers as needed
    • Proactively communicate consistently, clearly, and honestly
    • Ability to provide direct supervision to testing personnel.
    • Ability to analyze and problem solve complex issues that impact test performance
    • Strong analysis and problem solving skills
    • Strong technical skills and job and industry knowledge
    • Strong project management abilities
    • Ability to respond to change with flexibility and to adapt quickly to evolving circumstances
    • Able to integrate and apply feedback in a professional manner
    • Able to prioritize and drive to results with a high emphasis on quality
    • Ability to work as part of a team

Physical Demands and Working Environment

    • Hours and days may vary depending on operational needs
    • Standing or sitting for long periods of time may be necessary
    • May be exposed to hazardous materials, blood specimens and instruments with moving parts, heating or freezing elements, and high speed centrifugation
    • Repetitive manual pipetting may be necessary
    • Some lifting (up to 25 pounds) may be necessary
Based on the role, colleagues may be eligible to participate in an annual bonus plan tied to company and individual performance, or an incentive plan. We also offer a long-term incentive plan to align company and colleague success over time.

In addition, GRAIL offers a progressive benefit package, including flexible time-off, a 401k with a company match, and alongside our medical, dental, vision plans, carefully selected mindfulness offerings.

GRAIL is an Equal Employment Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. We will reasonably accommodate all individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. GRAIL maintains a drug-free workplace.