Senior Equipment Engineer #4088
Durham, NC
Research & Development – Lab Operations /
Full-Time /
On-site
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.
We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.
GRAIL is headquartered in Menlo Park, California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.
For more information, please visit grail.com.
GRAIL is seeking a Sr. Equipment Engineer for the Engineering Operations team. As a Sr. Equipment Engineer, you will provide site-wide support for clinical and non-clinical operations activities while implementing global solutions aligned with GRAIL’s business goals. Responsibilities will include the aspects of GRAIL's asset lifecycle program involving technical engineering support surrounding onboarding, qualification, maintenance, and overall performance of cutting-edge laboratory equipment and may include aspects of preventive maintenance, predictive maintenance, corrective maintenance, projects, etc. along with documenting activities in accordance with regulatory compliance guidelines. An ideal candidate will be experienced in liquid handling and next generation sequencing platforms, equipment validation, project management, and establishing support processes in accordance with regulatory compliance guidelines. This position will be working in close collaboration with the clinical and non-clinical lab staff and multi-functional teams. Strong interpersonal and troubleshooting skills are essential for success in this position.
This is a full time, onsite position working in the Research Triangle Park, NC lab.
1st Shift Start Time: 8:00am EST - Monday to Friday
Work on holidays may be required
On-call will be required
Working hours may be temporarily adjusted due to business demands, training, travel, and other events.
Responsibilities:
- Lead and execute Equipment Lifecycle Management processes and procedures by supporting and maintaining equipment records for traceability purposes in compliance with CLIA/CAP and ISO 13485 requirements
- Maintain Asset Management System to support internal Equipment Program processes and procedures
- Guides efforts to ensure reliability and maintainability of equipment, processes, mechanical, electrical, control, and safety/security systems following cGMP/GLP and Quality Management System (eQMS) guidelines
- Defines, develops, administers, and refines the Asset Management preventive/predictive maintenance programs
- Reduce and improve unplanned maintenance wherever feasible, assuring efficient and productive operation of equipment. Prolong the economic life of assets at the lowest practical cost
- Lead and executes cost saving initiatives and/or strategic long-term issues affecting the organization
- Lead and executes engineered solutions to mitigate repetitive failures that adversely affect plant availability, performance, capacity, quality, cost, or regulatory compliance
- Respond and solve equipment related issues in a timely manner
- Lead and executes failure reporting; analysis and corrective actions systems
- Create and update: procedures, work instructions, guidelines, and testing documents such as installation / operational / verifications, standard operating procedures (SOP)
- Lead and execute root cause investigations that drive for resolutions to completion.
- Demonstrate flexibility in work schedule and can adjust priorities as needed
- Manage and source vendors to support qualifications, installations, calibrations, investigations, upgrades, preventive maintenance (PM), and/or repairs as needed
- Participate, be a role model, and adhere to GRAIL’s policies and guidelines
- Preparation of reports, metrics, and other tracking tools measuring / allowing for success
- Provide technical training, support in the creation of new training, and transfer knowledge to fellow engineers and laboratory operators
- Lead investigations and act as a subject matter expert in NCRs, CAPAs, and associated quality and technical investigations
- Work closely with quality and regulatory to determine, include, implement and follow the required policies, requirements, and procedures for equipment lifecycle events
Preferred Qualifications:
- 5+ years of related experience with a BS/BA or higher degree in Engineering or equivalent work experience
- 5+ years experience troubleshooting and maintaining laboratory equipment.
- 3+ years experience maintaining low volume automated liquid handling systems (e.g. MultiFlo/Bravo, STAR/STARlet, Echo, Lynx, Lunatic, high throughput NGS sequencers)
- 3+ years experience with Laboratory Information Management Systems (LIMS), Manufacturing Management Systems (MES), Customer Relationship Management (CRM) software
- 3+ years experience with data analysis techniques including statistical process control, OEE, reliability modeling and prediction, RCA techniques, and/or six sigma methodology
- 3+ years experience using an asset computerized maintenance management system (CMMS)
- 3+ years experience project management
- Demonstrated ability to successfully lead, coach, and mentor
- Excellent communication skills to work as a leader and provide internal customer support
- Excellent time management skills to support a fast-paced working environment
- Excellent industrial, electrical, and mechanical knowledge
- Ability to work independently and as part of a team
Physical Demands & Working Environment
- Regularly required to stand, sit, walk, climb stairs/ladders, kneel, crouch, and wear safety gear.
- Hours and days may vary depending on operational needs.
- Working with dry ice may be necessary.
- Standing or sitting for long periods of time may be necessary.
- May be exposed to hazardous materials, blood specimens and instruments with moving parts, heating or freezing elements, and high speed centrifugation.
- Must occasionally lift and / or move up to 10 pounds.
- Must occasionally lift and/or move up to 25 pounds.
- Must occasionally lift and/or move up to 50 pounds.
- Travel may be required, up to 10% of the time.
The expected, full-time, annual base pay scale for this position is $91,000 - $114,000. Actual base pay will consider skills, experience, and location.
Based on the role, colleagues may be eligible to participate in an annual bonus plan tied to company and individual performance, or an incentive plan. We also offer a long-term incentive plan to align company and colleague success over time.
In addition, GRAIL offers a progressive benefit package, including flexible time-off, a 401k with a company match, and alongside our medical, dental, vision plans, carefully selected mindfulness offerings.
GRAIL is an Equal Employment Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. We will reasonably accommodate all individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. GRAIL maintains a drug-free workplace.
