Associate Director, Outcomes Research and Health Economics - #2160

London, UK /
Clinical Development and Medical Affairs /
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. GRAIL, LLC is a wholly-owned subsidiary of Illumina, Inc. (NASDAQ:ILMN). For more information, please visit

We are excited to be offering this opportunity to take a senior role in the Cancer Intelligence & Engagement team based (flexibly) in London to support the ongoing value proposition for multi-cancer early detection as a screening tool in the NHS.

Purpose of Role

Work as part of the UK team and with diverse and cross-functional teams to develop and deliver our value-evidence strategy, specifically driving all necessary work to underpin the health economics analysis plan for NHS-Galleri. Additionally to use your exceptional knowledge of the UK cancer screening landscape and modeling to lead analyses to support publications and evidence documentation.

Key Responsibilities

    • Lead the UK health economic analysis plan for the NHS-Galleri trial, working closely with GRAIL’s HEOR team
    • Commission and oversee all GRAIL-funded UK health economics work packages, ensuring completion of high quality, timely outputs and manage external consultants.
    • Act as the lead contact for NHSE health economists and ensure productive and effective working relationships with our NHS-commissioned partners.
    • Apply knowledge and understanding of NHS data sources to ensure appropriate datasets are selected and accessed for analysis
    • Use your relevant networks and knowledge of the literature to understand and overcome implementation challenges, creating supportive evidence where appropriate
    • Generate novel ideas for research projects in support of NHS implementation of MCED screening and symptomatic applications. 
    • Undertake analyses, programming, literature reviews and evidence syntheses
    • Contribute to writing manuscripts focused on UK health economics and epidemiology, as well as support of NHS delivery. 
    • Contribute to the development of comms materials (e.g. presentations), to communicate the HEOR argument around MCED screening technology. 
    • Support cross-organisation initiatives, working at a senior level with internal and external stakeholders including our senior academic partners. 
    • Support timely execution of the publication plan, including liaising with external academics and US GRAIL colleagues.
    • Contribute to a positive, inquisitive and collaborative UK team culture
    • Maintain an awareness of relevant new publications, and pertinent literature.
    • Point of contact for UK health economic related queries.

Experience Required

    • A PhD or equivalent, and considerable years’ experience working in a related discipline such as epidemiology, statistics, public health, health economics or medicine
    • Deep knowledge and understanding of cancer screening and/or early diagnosis and the evidence required to support implementation of early detection methods
    • Good understanding of Health Technology Assessment processes (e.g. NICE technology appraisals).
    • Excellent written and verbal communication skills with the ability to explain complex ideas clearly.
    • Experience with commonly used modeling methods for cost-effectiveness analysis such as Markov models and/or discrete event simulation.
    • A good knowledge of cancer care provision within the NHS and interest in the developing landscape
    • Ability to programme in R
    • Commercial experience and/ or close involvement in running clinical cancer trials
    • Knowledge of NICE processes and levels of required evidence
    • Previous experience of management of external consultancies
    • Knowledge of cancer biology
    • Understanding of GDPR and experience of data access processes.
GRAIL is an Equal Employment Employer and does not discriminate on the basis of race, colour, religion, sex, sexual orientation, gender identity, national origin, disability, or any other legally protected status. We want people from all walks of life to feel valued for their individuality, thrive in our business and share a sense of belonging.  If you have a disability or special need that requires accommodation, please contact us.