Analytical RA II
B4 - CA, MV
Process Development & Manufacturing – Process Development /
Full-Time /
On-site
About IGM Biosciences, Inc.
IGM Biosciences (Nasdaq: IGMS) is a clinical-stage biotechnology company committed to developing and delivering a new class of medicines to treat patients with cancer and autoimmune and inflammatory diseases. The Company’s pipeline of clinical and preclinical assets is based on the IgM antibody, which has 10 binding sites, compared to conventional IgG antibodies with only 2 binding sites. We have created unique IgM antibodies with high selectivity, affinity, and avidity that may redefine what is possible for therapeutic antibody medicines. We believe our proprietary IgM antibody technology platform is particularly well suited for developing T cell engagers and receptor cross-linking agonists. The Company also has an exclusive worldwide collaboration agreement with Sanofi to create, develop, manufacture, and commercialize IgM antibody agonists against oncology, immunology, and inflammation targets. For more information, please visit www.igmbio.com.
IgM Antibodies and Autoimmune and Inflammatory Diseases
Antibody treatments have revolutionized outcomes for patients with autoimmune and inflammatory diseases. We are committed to exploring how our IgM antibody platform's unique structure and binding properties can improve outcomes for patients with these serious conditions.
IgM Antibodies and Oncology
The potential of our IgM antibodies drives our focus on oncology. Leveraging the power of avidity and the strong and durable binding of our IgM antibodies, we are developing new treatment options for cancer patients. Our initial efforts in this field are centered around the broad application of IgM antibodies to activate receptors, triggering the programmed death of cancer cells.
We are seeking an experienced, hands-on individual to join our analytical team in the role of Analytical RA II. In this role, you will support analytical method development and manufacture process development activities for the IGM biotherapeutics IND portfolio. You must be willing to learn and train across broad analytical areas, be organized, have the ability to multi-task, and have a strong desire to work in a team-oriented, dynamic environment.
Responsibilities
- Following SOPs to characterize antibodies with Spectroscopy (UV-VIS/A280), Plate Based Assays (ELISAs, Cell Based Potency), Gels (SDS-PAGE, Western Blot), HPLC (SEC, RP), Capillary Based methods (CE-SDS, cIEF) and other biophysical methods.
- Support antibody analytical method development, and routine testing for process development, formulation development and stability studies.
- Operate and help maintain lab equipment including but not limited to Plate readers, plate washers, UV-VIS and Liquid Chromatography instruments.
- Support sample shipping, progress tracking, receiving and inventory.
- Maintain an organized analytical lab environment, complying with Fed and Cal safety regulations.
- Prepare lap plans and record experiments using an Electronic Lab Notebook
- Prepare buffers and handle protein samples with aseptic techniques.
- Help prepare SOPs, protocols, and technical documents.
- Analyze scientific/technical data and present data in project team meetings
Qualifications:
- Level commensurate with experience
- Chemistry, Biology, or related background, BS with 2+ years, MS with 1+ years of hands-on Bioanalytical Lab experience, preferably in the biotech/biopharmaceutical settings.
- Experience with Spectroscopy (UV-VIS/A280), Plate Based Assays (ELISAs, Cell Based Potency) and Gels (SDS-PAGE, Western Blot) is a must.
- Experience with biologics and aseptic sample handling is required.
- Experience with other analytical methods such as HPLC (SEC, RP) and Capillary Based methods (CE-SDS, cIEF) is a plus
- Able to work efficiently on multiple projects simultaneously.
- Willingness to learn new skills.
- Strong interpersonal and communication skills are a must.
- Able to lift up to 20lbs and work at the lab bench for extended periods of time.
- Must be able to commute to Mountain View.
- We offer a fast-paced, collaborative, team-based, work environment.
$88,000 - $101,000 a year
This range reflects the job's characteristics, such as required skills and qualifications, and is based on the office location noted in this job posting. The range may also be adjusted based on the applicant's geographic location.
Actual individual pay is determined by demonstrated experience and internal equity alignment.
One of our top priorities is to maintain the health and well-being of our employees and their families. To achieve this goal, we offer comprehensive benefits with a variety of options:
· Medical, dental and vision insurance.
· The full premium amount for our employees and their dependents is covered by IGM
· FSA (Flexible Spending Account) or HSA (Health Savings Account)
· STD, LTD, Basic Life and AD&D Insurance, Supplemental Life and AD&D Insurance
· Voluntary Life Insurance and Disability
· 401(k) Plan with Employer Match
· 3 Weeks of Paid Time Off, 5 sick days per year, 12 holidays
· Cell phone & internet subsidy
· Employee Referral Bonus Program
· Annual training budget for professional development
· Commuter Benefit
· Annual bonus program
· New hire stock
· Annual refresh grants
· ESPP (Employee Stock Purchase Plan)
