Senior Research Associate / Associate Scientist, Translational Research
Mountain View, CA /
Scientific Research & Development – Preclinical Sciences /
Full-Time
/ On-site
About IGM Biosciences, Inc.
IGM Biosciences (Nasdaq: IGMS) is a clinical-stage biotechnology company committed to developing and delivering a new class of medicines to treat patients with cancer, infectious diseases, and autoimmune and inflammatory diseases. The Company’s pipeline of clinical and preclinical assets is based on the IgM antibody, which has 10 binding sites compared to conventional IgG antibodies with only 2 binding sites. We have created a proprietary IgM antibody technology platform that we believe is particularly well suited for developing T cell engagers, receptor cross-linking agonists, targeted cytokines, and target neutralizers. The Company also has an exclusive worldwide collaboration agreement with Sanofi to create, develop, manufacture, and commercialize IgM antibody agonists against oncology and immunology, and inflammation targets. For more information, please visit www.igmbio.com.
IgM Antibodies and Autoimmune and Inflammatory Diseases
Antibody treatments have revolutionized outcomes for patients with autoimmune and inflammatory diseases, and IgMs are the first antibody defense against a pathogen infection. We are committed to exploring how the unique structure and binding properties of our IgM platform can improve outcomes for patients with these serious conditions.
IgM Antibodies and Oncology
IGM Biosciences has a T cell engager program, a receptor cross-linking agonist program and a targeted cytokine program in clinical studies for the treatment of patients with solid tumors and hematological malignancies.
Position Summary
We are looking for a talented and self-motivated Senior Research Associate/Associate Scientist with a background in immunology and/or inflammation to join our growing Translational Research team. The successful candidate will play an integral role in the preclinical development of novel antibody-based therapeutics in a variety of disease areas and at various stages of development. This is a hands-on laboratory position that necessitates dedication and dependability. The candidate will perform standard human and animal cell-based immuno-assays, multi-dimensional flow cytometry, common molecular techniques, constantly improve work practices, and work productively as part of a team. Experience in autoimmunity is desirable.
Responsibilities:
- Independently designs and executes experiments that support preclinical research activities and project goals
- Conduct cell-based in vitro assays using primary cells (including human, mouse and non-human primates) and cell culture of mammalian cell lines
- Perform multicolor flow cytometry, ELISA or other methods of cytokine/analyte analysis
- Proactively troubleshoots technical issues, recommends alternative/new methods and techniques based on literature searches, and seeks out others to discuss potential solutions to problems
- Communicates work effectively, orally and in writing, presenting data in group meetings
- Thoroughly and accurately documents experimental activities in laboratory notebooks
- Presentation of results at internal meetings
Requirements:
- BS, MS or equivalent degree in Immunology, Cell Biology or related scientific discipline
- SRA: BS with 8+ years or MS with 4+ years of experience.
- Associate Scientist: BS with 11+ years or MS with 6+ years of experience.
- Industry experience with biologics is preferred.
- Experience with multicolor flow cytometry (10+ colors), ELISA and other methods of cytokine/analyte analysis
- Ability to perform high quality functional assays including primary cell isolation, co-culture assays, and molecular techniques (e.g. qRT-PCR)
- Experience in with in vivo mouse models of autoimmune disease, and human in vitro immuno-assays with primary cells is a plus
- Proficient with basic computer programs routinely used in a lab such as MS Word, Excel, and PowerPoint, GraphPad Prism, and FlowJo
- Highly organized with reliable time-keeping skills and able to maintain a detailed and well-organized e-notebook
- Excellent interpersonal and communication skills
- Being a team player and respectful of others is a must.
- Ability to thrive in a fast-paced, small start-up environment.
- Must be able to commute to Mountain View.
Salary Range:
The typical annual salary range for this full-time position is $95,000 - $130,000, plus eligibility for cash and equity incentives.
This range reflects the characteristics of the job, such as required skills and qualifications, and is based on the office location noted in this job posting. The range may also be adjusted based on the applicant's geographic location.
Actual individual pay is determined by demonstrated experience and internal equity alignment.
We offer a fast-paced, collaborative, team-based, work environment.
One of our top priorities is to maintain the health and well-being of our employees and their families. To achieve this goal, we offer comprehensive benefits with a variety of options:
· Medical, dental and vision insurance.
· The full premium amount for our employees and their dependents is covered by IGM
· FSA (Flexible Spending Account)
· STD, LTD, Basic Life and AD&D Insurance, Supplemental Life and AD&D Insurance
· 401(k) Plan
· 120 hours of Paid Time Off, 5 sick days per year, 11 holidays
· Cell phone & internet subsidy
· Employee Referral Bonus Program
· Annual training budget for professional development
· Commuter Benefit
· Annual bonus program
· New hire stock options
IGM is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status, and veteran status. All qualified applicants will receive consideration for employment.
