Scientist II, Protein Sciences
Seattle, WA
Protein Sciences /
Full-time /
On-site
About InduPro
InduPro, Inc. is bringing life-changing therapies to patients through novel cell-surface platform technologies. We are defining and manipulating protein interactions beyond natural signaling paradigms. InduPro platforms integrate inherent protein proximity at the cell surface with the ability to manipulate protein pairings via induced protein proximity to create novel signaling pathways and logic gates. Our culture fosters innovation at every level.
The Opportunity
We are seeking an enthusiastic and highly motivated conjugation scientist to join InduPro Protein Sciences group to help expedite and enable our therapeutic opportunities via induced proximity strategies. As part of an exciting startup, you will support Antibody Drug Conjugate (ADC)/protein production and characterization efforts and execute on strategic workplans to advance drug candidates from discovery into IND filing. You will also work cross-functionally with other teams in a dynamic and collaborative environment.
Key Responsibilities
- Develop and optimize ADC conjugation protocol/process, run routine ADC conjugation work
- Perform routine protein production of bi/multi-specific antibodies and engineered proteins
- Develop diverse analytical tools for ADC and protein biophysical characterization
- Troubleshoot technical challenges related to ADC/protein purification and production, implement solutions to optimize experimental workflows
- Maintain accurate and up-to-date records of experimental procedures, results, and data analysis, and contribute to the preparation of scientific reports and publications
- Strong communication and collaboration with interdisciplinary teams to provide protein science support and contribute to the design and execution of experiments aimed at achieving project goals
- Interact with external stakeholders, such as contract research organizations and collaborators, to commission work as needed
- Performs other duties as assigned
Education & Experience
- Ph.D. with 2+ years of relevant industry experience, M.S. with 5+ years relevant industry experience, or B.S. with 10+ years of relevant industry experience in Biochemistry, Biology, or a related field
- Proficiency in small-, medium- and large-scale ADC conjugation and protein labelling process
- Familiarity with different conjugation techniques (including ThioMab-, glycan- and/or enzyme-based site-specific conjugation) is desirable
- Experience on ADC/protein mass spec analysis and developability assays are plus
- Knowledge of protein structure and automation is helpful
- Demonstrated expertise in protein purification with different chromatography methods
- Strong critical thinking and evaluative skills
- Decisive results-oriented individual who is flexible, team-oriented, creative, and able to excel in a multi-project, fast-paced environment
Physical Work Requirements
- Reasonable periods of standing, reaching and bending while working in the lab
- Reasonable periods of sitting at a desk and working on a computer
Travel Requirements
- This position does not generally require travel.
- Physical presence at the InduPro worksite is required for this role. At InduPro we believe that physical presence helps enhance collaboration, innovation, productivity, employee well-being, employee engagement, and Company culture.
$120,000 - $145,000 a year
The anticipated salary range for this position is $120,000 to $145,000. The final salary will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etc.
On top of base salary, we offer comprehensive benefits, bonus, and equity. If this range doesn't match your expectations, please still apply because we may have another opportunity for you.
Benefits
At InduPro we believe that being face to face helps enhance collaboration, innovation, productivity, employee well-being, employee engagement, and Company culture.
Every member of the InduPro team plays a role in shaping our science and our culture in a dynamic startup environment. We offer a competitive total compensation package, including stock options, participation in an annual performance bonus incentive program, a comprehensive benefits package, paid time off, and exciting opportunities for professional development.
Benefits include medical, dental, and vision coverage; company-paid life and disability insurance; supplemental life and disability insurance; voluntary accident, critical illness, and hospital indemnity insurance; a 401(k) plan with employer matching contributions; flexible spending accounts; an employee assistance program; flexible paid time off; 10 paid company holidays; and employee access to voluntary auto, home, legal, and pet insurance.
InduPro, Inc. is an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, age, gender identity, sexual orientation, color, religion, sex, marital status, national origin, protected veteran status, disability, or any other status protected by federal, state, or local law.
