Senior Scientist, Oligonucleotide Chemistry

40 Erie St. Cambridge, MA 02139
Research & Development – RNA/Chemistry
At Intellia, we are revolutionizing medicine by harnessing the power of genome editing to develop potential cures. We bring new hope for people living with conditions including cancer, genetic disorders, viral infections, inflammatory disorders and many more.

Intellia Therapeutics is seeking an experienced Senior Scientist to join the RNA Chemistry Team, which is responsible for the production of synthetic oligonucleotides. This individual will be involved in a complete production process for the identification, implementation & fulfillment of synthesis, purification and reaction scheme analytical characterization and method development of oligonucleotides.

Execute synthesis, deprotection, purification, & downstream processing of oligonucleotides.
Operate, maintain & calibrate synthesis platforms and other scientific equipment.
Design & implement semi-preparative and analytical HPLC and LC-MS quality control processes.
Continuous synthetic oligonucleotide method and process development.
Solid decision-making on product path with the ability to work independently and collaboratively while problem-solving.
Demonstrate lab competency in preparing reagents and buffers & handling chemicals.
Write and follow standard operating procedures and process improvement documents.
Documentation of results and data analysis.
Ensure safety and product quality are paramount throughout the laboratory environment.

Ph.D. in Chemistry, Biochemistry, Biochemical or Chemical engineering or related discipline with at least 3 years experience, preferably in an industrial drug discovery setting.
MS with 8 years and BS with 10 years of experience will also be considered.
Basic computer skills including MS Office Suite.

Attention to detail
Exceptional time management
Effective communicator
Capable of repetitive tasks and performing other duties as assigned
What Intellia Stands For?

At Intellia, our mission is to develop potentially curative genome editing treatments that can positively transform the lives of people living with severe and life-threating diseases.

We push boundaries. We are focused on positively disrupting health care treatment of patients with genomic diseases. The values we live by and drivers we look for are:

- One is respect for individuals; our unique qualities and strengths; our own ways to understand, learn and improve. One is our single-minded determination to excel; to succeed together. One is you and us – trusting and counting on every single one of us.

- Explore because we seek new ways to tackle disease. Explore with unbounded minds…free from assumptions, open to ideas. Explore by staying curious, by pushing boundaries, overcoming obstacles. Explore means thinking of new ways.

- Disrupt by thinking courageously…and creating a better future. Disrupt by defying conformity; interrogating the status quo; questioning our momentum. Disrupt with challenging thoughts…with that breed of skepticism that shows you have better solutions.

- Deliver with your focus on the objective and your determination to complete the task. Deliver by advancing relentlessly and by maintaining high standards…even when nobody is watching. Deliver by staying accountable and pulling your weight. Deliver because patients are counting on us to make the promise reality. Get it done.
POSITION: Full-Time, Exempt
EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.