Head of / Director of Formulation

Remote /
Product Development & Manufacturing /
Full Time
/ Hybrid
Loyal is an early stage company developing drugs to help dogs live longer, healthier lives. We apply innovative approaches to tackling aging as a disease that can be slowed and improved with medicines. Loyal is an early stage start-up company and is well funded by top venture capitalists and angels.

Loyal is hiring a Director of Formulation. You will lead the planning and execution of drug product development from pre-formulation, formulation development and characterization, production of pre-clinical and clinical trial materials. 

Loyal is founded and led by a first-gen, female CEO – we encourage and look forward to diverse applicants. 

You will:

    • Lead the planning and execution of drug product development from pre-formulation, formulation development and characterization to production of pre-clinical and clinical trial materials
    • Develop formulations alongside Contract Development and Manufacturing Organizations (CDMOs). May include overseeing and performing hands-on development experiments for drug product formulations in our in-house lab.
    • Manage collaborations with CDMOs
    • Build and maintain relationships with competent CDMOs
    • Negotiate supply and service agreements
    • Perform technical due diligence of CDMO proposals, protocols, data and reports
    • Provide strategic and tactical input to the overall product development plans including raw material sourcing, formulation development, quality, and manufacturing aspects. 
    • Proactively identify issues, risks, and opportunities to improve and optimize product development and manufacturing processes 
    • Author/review CMC sections for regulatory filings and, if requested, interact with regulatory agencies to answer questions

How you work and think:

    • You take responsibility for leadership and delivery on your area of expertise
    • You will do the work yourself - this role will be the only formulation person in the team, although we have consultants to provide support
    • You acknowledge all potential ideas and solutions regardless of source
    • You can successfully lead intradepartmental and cross-functional collaboration meetings and give technical presentations
    • You enjoy seeing your work as part of the bigger picture
    • You have a desire to mentor and support others in your team
    • You have a startup mindset: you work fast, are low ego, are comfortable with uncertainty and are collaborative
    • You are able to communicate options, risks and benefits of various approaches in a clear and concise manner
    • You demonstrate adaptability, creativity and are a high performer in risk-assessment and strategic thinking
    • You are comfortable managing others- laterally, up, and potentially direct reports
    • You are detail oriented, disciplined, naturally seek ownership and responsibility, and are happy working on a mix of the fascinating and the mundane
    • You love to learn and excited to self-teach random topics as relevant to the company and projects
    • You have the ability to meet or beat rapid deadlines and work well under pressure
    • You have a growth mindset, value transparency, and seek out feedback and iteration cycles
    • Having familiarity with G suite applications (e.g., Sheets, Slides, etc.) is a bonus

About you:

    • You have a degree or equivalent experience in Chemistry, Chemical Engineering, or a related physical science
    • You have 4+ years of experience in a similar role and a successful track record of executing drug product development
    • You have 10+ years of hands-on formulation experience (tablets, capsules, and other solid oral delivery forms)
    • Having experience of injectable and long-acting formulations is a benefit but not essential.
    • You have significant experience managing CDMOs or equivalent
    • You have industry expertise in key CMC areas, including small molecule oral tablet formulation development, technical transfers, scale up and manufacturing.
    • You have proven team development skills

Why join us?

    • Full-time position either remote or based in San Francisco, CA, with flexible hybrid work opportunities
    • Full coverage platinum health insurance (medical, dental and vision) for you and your dependents
    • 401k
    • Generous monthly stipend package for wellness, learning, and fitness
    • Stipend for home office set-up
    • Flexible paid time off & 28 days of whole company holiday per year
    • Paw-ternity leave for pet adoption
    • Dog-friendly office
    • Generous relocation package
    • Welcome kits with Loyal swag
    • Our cash compensation amount for this role is targeted at $110,000 - $200,000/yr. Final offer amounts are determined by candidate experience, expertise, and geographic location and may vary slightly from the above mentioned amounts.
    • Start ASAP
Our Values

Lean into moonshots | We do not settle for incremental change. We have the bravery to take risks and shoot for the impact we want to have.

Opportunity is at the intersection | We lean into combining disciplines, expertises, and perspectives not normally adjacent. We design our organization to facilitate cross-pollination and cross-collaboration. We reject silos.
 
Expertise without ego | Titles do not determine who has a voice. We work on hard, technical problems and have a ton of fun while at it.
 
Learning by doing | Our path is novel and many things we are doing have never been done before. We lean into MVPs and are open to unexpected outcomes.
 
Transparency and rejecting paternalism | We value leading with context. We equip people with the context and background necessary to make their own decisions and act in the best interest of Loyal. Empower team to succeed.

Empathy and respect for all life | Our patients are not just numbers. Our work is intentional, thoughtful, and guided by respect for life. We take our responsibility to pets and pet parents seriously.