Senior Medical Director/Medical Director, Medical Affairs

Conshohocken, PA
Medical Affairs /
Full Time
/ Hybrid
Position Title: Senior Medical Director/ Medical Director, Medical Affairs

Department: Global Medical Affairs

Location: Primary – HQ position - Can operate remote at times but would have to be in HQ regularly (~2-3 days/week)

Reports To: Executive Medical Director, Medical Affairs

The Senior Medical Director, Medical Affairs (MA) at Madrigal is responsible for the execution of medical activities within the context of the US health care environment that, depending on specific areas of responsibility, may include medical strategy development and execution; medical content development and review; clinical data analysis, interpretation and publication; exploratory data analysis; support of medical and promotional content review and approval; review of standard response documents; development of and execution of advisory boards and other approaches to gain input from thought leaders (TL) and other experts; setting and executing the medication education strategy; clinical training and insights generation; and scientific exchange and collaboration.

This position will also represent the global MA function within cross functional teams and initiatives at Madrigal and in external customer facing engagements.

Responsibilities of Role:

Oversee content development of clinical and other data for Field Medical (MSLs), advisory boards, heath system teams including proactive, reactive and training material

Train Field Medical Affairs team on relevant disease state topics and clinical trial data

Participate in the design, execution and monitoring of medical strategy, gap analysis, plans and tactics spanning the life cycle of resmetirom and other development compounds

Deliver or provide support for clinical data and other presentations at Regional and National Advisory Board meetings and gain feedback from advisors

Provide formal promotional and medical review

Maintain scientific knowledge of therapy area and competitors and appropriately alert important new data or information relevant to the TA strategy teams

Support implementation of IIS program and registry

Serve as a subject matter expert and resource for medical team but also in support of marketing and market access activities as needed

Provide review of all standard response documents as requested by medical information

Serve on Publication Planning Group, where relevant

Review and provide comments to abstracts, posters, and manuscripts, including primary, secondary and HEOR publications

Prepare and support presenting external authors

Drive the exploratory data analysis within the evidence generation process

Contribute to the strategy of identifying data sources to answer complex clinical questions according to the medical strategy (including registries)

Support abstract, poster and manuscript development with publications team and clinical development

Provide expert input strategy and tactical execution including field medical insights and advisory boards

Scientific exchange/engagement and scientific communications/collaboration

Liaise with Legal and Finance for assigned projects, to ensure projects are promptly reviewed and approved

Maintain a record of vendors’ signed SOWs and POs

Lead assigned projects and deliver according to agreed timelines, quality, and budget

Required Experience:

An advanced Doctoral degree in health sciences (e.g., PharmD, MD, DO, DPN, PhD), with a thorough grasp of the pharmaceutical industry

Minimum of 5 years of relevant Medical Affairs experience in Pharma/Biotech industry with 2 years in liver disease

Understanding of and/or previous experience with Phase I - III and/or Phase IV drug development preferred

Post-marketing medical evidence generation, including expertise in controlled and observational study designs, data analysis, and clinical/health economic interpretations

Considerable experience in the principles and techniques of data analysis, interpretation and clinical relevance, and medical writing

Proven record in developing strong relationships with external constituents (therapeutic area experts, external organizations, etc.) preferred

Proven track record of meeting or exceeding objectives and goals

Excellent strategic planning, organizational and communication skills

Knowledge of relevant health care systems, the evolving landscape, regulatory and payer environment

Ability to navigate complex and challenging situations and flex and thrive in an ambiguous environment

May require up to 30% travel for work

Please be aware that we are currently receiving numerous reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals’ Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal’s name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process. Interviews with Madrigal are conducted via the Zoom platform.
Please also note that any correspondence with regard to employment would come from an authorized email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses, with Madrigal misspelled, have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for Madrigal we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks.