Senior Medical Director/Medical Director, Medical Affairs
Conshohocken, PA
Medical Affairs /
Full Time
/ Hybrid
Position Title: Senior Medical Director/ Medical Director, Medical Affairs
Department: Global Medical Affairs
Location: Primary – HQ position - Can operate remote at times but would have to be in HQ regularly (~2-3 days/week)
Reports To: Executive Medical Director, Medical Affairs
The Senior Medical Director, Medical Affairs (MA) at Madrigal is responsible for the execution of medical activities within the context of the US health care environment that, depending on specific areas of responsibility, may include medical strategy development and execution; medical content development and review; clinical data analysis, interpretation and publication; exploratory data analysis; support of medical and promotional content review and approval; review of standard response documents; development of and execution of advisory boards and other approaches to gain input from thought leaders (TL) and other experts; setting and executing the medication education strategy; clinical training and insights generation; and scientific exchange and collaboration.
This position will also represent the global MA function within cross functional teams and initiatives at Madrigal and in external customer facing engagements.
Responsibilities of Role:
Oversee content development of clinical and other data for Field Medical (MSLs), advisory boards, heath system teams including proactive, reactive and training material
Train Field Medical Affairs team on relevant disease state topics and clinical trial data
Participate in the design, execution and monitoring of medical strategy, gap analysis, plans and tactics spanning the life cycle of resmetirom and other development compounds
Deliver or provide support for clinical data and other presentations at Regional and National Advisory Board meetings and gain feedback from advisors
Provide formal promotional and medical review
Maintain scientific knowledge of therapy area and competitors and appropriately alert important new data or information relevant to the TA strategy teams
Support implementation of IIS program and registry
Serve as a subject matter expert and resource for medical team but also in support of marketing and market access activities as needed
Provide review of all standard response documents as requested by medical information
Serve on Publication Planning Group, where relevant
Review and provide comments to abstracts, posters, and manuscripts, including primary, secondary and HEOR publications
Prepare and support presenting external authors
Drive the exploratory data analysis within the evidence generation process
Contribute to the strategy of identifying data sources to answer complex clinical questions according to the medical strategy (including registries)
Support abstract, poster and manuscript development with publications team and clinical development
Provide expert input strategy and tactical execution including field medical insights and advisory boards
Scientific exchange/engagement and scientific communications/collaboration
Liaise with Legal and Finance for assigned projects, to ensure projects are promptly reviewed and approved
Maintain a record of vendors’ signed SOWs and POs
Lead assigned projects and deliver according to agreed timelines, quality, and budget
Required Experience:
An advanced Doctoral degree in health sciences (e.g., PharmD, MD, DO, DPN, PhD), with a thorough grasp of the pharmaceutical industry
Minimum of 5 years of relevant Medical Affairs experience in Pharma/Biotech industry with 2 years in liver disease
Understanding of and/or previous experience with Phase I - III and/or Phase IV drug development preferred
Post-marketing medical evidence generation, including expertise in controlled and observational study designs, data analysis, and clinical/health economic interpretations
Considerable experience in the principles and techniques of data analysis, interpretation and clinical relevance, and medical writing
Proven record in developing strong relationships with external constituents (therapeutic area experts, external organizations, etc.) preferred
Proven track record of meeting or exceeding objectives and goals
Excellent strategic planning, organizational and communication skills
Knowledge of relevant health care systems, the evolving landscape, regulatory and payer environment
Ability to navigate complex and challenging situations and flex and thrive in an ambiguous environment
May require up to 30% travel for work
Please be aware that we are currently receiving numerous reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals’ Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal’s name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process. Interviews with Madrigal are conducted via the Zoom platform.
Please also note that any correspondence with regard to employment would come from an authorized madrigalpharma.com email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses, with Madrigal misspelled, have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for Madrigal we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks.
