Senior Manager/Associate Director, Commercial Data Management

Remote /
Commercial /
/ Remote
At Madrigal, we are committed to transforming treatment for patients with non-alcoholic steatohepatitis (NASH). NASH will soon become the leading cause of liver transplantation in the U.S., but there are currently no approved medications to treat the disease.

Madrigal's lead candidate, resmetirom, is a once daily, oral, thyroid hormone receptor (THR)-? selective agonist that is designed to target key underlying causes of NASH in the liver. Positive results from first of the two Phase 3 clinical trials of resmetirom in NASH were announced in January 2022 and results from a second Phase 3 clinical trial are expected in Q4 2022. Resmetirom is on track to launch in the U.S. towards the end of 2023.

Madrigal has established its leadership position in NASH by staying true to its science-driven foundation and building a company culture based on collaboration and trust. Our team members are focused on delivering results for the benefit of investors, healthcare providers, and, most importantly, patients. These values will remain central to Madrigal as the company grows and evolves its commercial capabilities to prepare for a potential first-to-market launch in NASH.

The Madrigal Story:
2004-2008:Madrigal founder Dr. Rebecca Taub studies THR-B agonism while working at Hoffmann-La Roche
2008: Madrigal predecessor company VIA Pharmaceuticals hires Dr. Taub and enters into a development agreement with Hoffmann-La Roche for resmetirom
2011: Madrigal is incorporated in Delaware and Ph 1 trial of resmetirom commences
2016: Phase 2 trial of resmetirom in NASH commences; Madrigal merges with Synta Pharmaceuticals and is listed on NASDAQ, and Dr. Paul Friedman named CEO and Rebecca Taub named CMO of Madrigal

2017-2018: Positive Ph 2 results in NASH help accelerate Madrigal's growth

2019: Madrigal commences Phase 3 “MAESTRO” program for resmetirom

2020: Madrigal hires Remy Sukhija as Chief Commercial Officer and begins building its commercial organization

2021: Madrigal continues to expand its executive team

2021-2022: Positive Phase 3 MAESTRO-NAFLD-1 resmetirom data announced

Madrigal's Commercial Team:
Madrigal's commercial team is in constant pursuit of excellence in what we do and the way we show-up, every day. Conducting our business in an honest and transparent fashion is of prime importance to us. We have a "business owner" mentality as we feel the awesome responsibility to do right by the opportunity we have been given to bring a potentially revolutionary therapy to patients and their healthcare providers. It is essential for each one us on the commercial team to have deep and up-to-date knowledge of resmetirom program and developments in NASH as we prepare to answer the needs of the patients and physicians we hope to serve with approval and launch of resmetirom in the U.S.

Position Summary:

The Senior Manager, Data Management, will play a key role in creating and executing Madrigal's Data Strategy in support of the commercialization of resmetirom in the U.S. and globally. This position will have the unique opportunity to shape the data management strategy for a new disease area (NASH). Will be instrumental in building capabilities and systems from the ground up to support Madrigal's first commercial launch. Tactically, execution will include developing and managing Madrigals Datawarehouse and MDM capabilities by identifying business requirements through mapping of key data-related projects. He/She will support the development of project scopes and identify key vendors, datasets, data warehouse architecture, and resources needed to fulfill business requirements. The position will serve as the day-to-day contact for external commercial operations/data analytics vendor(s) for data-related things. Major responsibilities will include overseeing the data warehouse's day-to-day operations, including integrating and managing specialty pharmacy, Hub, and 3rd party data sets.
He/She will coordinate closely with Sales Planning, Marketing, and other key functions to ensure appropriate internal and external vendor data access and visibility. Will be responsible for providing data quality through proactive management and timely resolution of any issues from the field teams and/or resulting analytics. The position will report into the Associate Director of data strategy & analytics

Job Requirements:
Lead the development of Madrigal's Data warehouse and Master Data Management systems and processes supporting Resmetirom Launch
Responsible for the creation and management of reporting tables in support of Madrigals BI/Reporting platform needs
Will be responsible for data quality and integrity by actively monitoring data quality and resolving data-related issues and disruptions
Manage day-to-day relations and operations of external data warehouse partner (Veeva)
Manage the data aggregator and data aggregation process across specialty pharmacy and Hub partners
Manage ETL processes for all vendor and 3rd party data
Responsible for the creation and management of reporting tables in support of Madrigals BI/Reporting platform needs
Manage data-related SLAs across Vendors
Support the design and execution of Madrigal's data strategy in support of key cross-functional launch activities with ownership of Data Management
Support business and IT teams through onboarding new data, defining data quality checks, and documenting business rules
Maintain an updated inventory of data assets and promote transparency, sharing, and utilization of data across the commercial organization
Support Sales Planning in addressing inquiries from internal and field-based teams and resolving issues (as needed)
Support the quarterly incentive compensation process in partnership with Sales Planning
Effectively communicate with internal stakeholders to build confidence in the accuracy and quality of data
Support the creation and management of Madrigal's Data Governance, ensuring all aspects of data visibility and sharing are compliant
Conducts ad-hoc analysis as needed
Required Skills & Abilities:

Able to drive multiple workstreams simultaneously and prioritize efforts to achieve objectives
Experience with relational databases (Redshift), ETL, CRM systems such as and Veeva, and master data management (MDM) systems. Experience with Veeva Nitro & Network a plus
Experience with BI/analytical tools like Tableau or PowerBI is strongly preferred
Technical fluency in SQL
Experience working in a specialty distribution model
Demonstrated expertise in handling patient-level data and familiarity with HIPAA law
Strong analytical, data analysis, and problem-solving ability
Work effectively with cross-functional partners, including medical, market access, marketing,                   
 regulatory, legal and compliance
Build strong relationships with key internal stakeholders and external partners
Possesses a natural curiosity and the ability to challenge the status quo
Experience presenting and simplifying complex topics for senior management
Self-motivated/Flexible and can thrive in a high-paced and lean environment

Education and Experience:

Bachelor's Degree, preferably in computer sciences, engineering, math, or other technical disciplines

Candidate must have at least 5 years of Pharmaceutical or Life Science experience within Data warehousing and analytics (open to candidates from consulting)
Experience managing an external data warehouse partner preferred
5+ years of experience in SQL, Relational databases
3+ years of experience in Data Visualization tools such as Tableau, Power B.I., etc.
Experience working with key commercial data providers such as Symphony, Veeva, and MMIT
Experience Implementing and managing data within a specialty pharmacy distribution model
Experience working in smaller companies and building a data warehouse from the ground up
Demonstrated expertise in handling patient-level data and familiarity with HIPAA laws
Knowledge of Sales Operations DCR and Incentive Compensation processes a plus
Product launch experience is a plus
An attractive compensation package will be offered to the successful candidate. It will include a competitive base salary and incentive bonus. A benefits package customary to the position will also be provided including 401k match, medical and dental.
Madrigal is an Equal Opportunity Employer and will judge all applicants based on their qualifications for the job, without regard to race, color, sex, religion, national origin, age, disability, sexual orientation, gender identity, protected veteran, disability status or any other characteristics protected by applicable federal, state or local law.
Unsolicited resumes from agencies should not be forwarded to Madrigal.
Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established.
Proof of full vaccination against COVID-19 prior to the start date is required.