Engineer - Mechanical

San Francisco
Mammoth Biosciences is harnessing the diversity of nature to power the next generation of CRISPR products. Through the discovery and development of novel CRISPR products. Through the discovery and development of novel CRISPR systems, the company is enabling the full potential of its platform to read and write the code of life. Mammoth aims to democratize disease detection with an easy and affordable point-of-care test that allows real-time and simultaneous detection of multiple conditions. By leveraging its internal research and development and exclusive licensing to Cas12, Cas13 and Cas14, Mammoth can provide enhanced diagnostics and genome editing for life science research, healthcare, agriculture, biodefense and more. Based in San Francisco, Mammoth Biosciences is co-founded by CRISPR pioneer Jennifer Doudna and principal founders Trevor Martin, Janice Chen, and Lucas Harrington. The firm is backed by top institutional investors including Mayfield, NFX, and 8VC, Decheng and leading individual investors including Brook Byers, Tim Cook, and Jeff Huber.

Be part of growing prototyping team at Mammoth: Execute CRISPR-based projects for product development

Designing, manufacturing, testing and troubleshooting prototype devices for proof-of-concept experiments

Think creatively about prototyping for diagnostic and CRISPR technologies


    • BS or MS in mechanical engineering, microelectronics/microfluidics or biomedical engineering and 2+ yrs relevant research experience in industry or academia
    • Strong background in miniaturizing molecular biology, analytical chemistry and genomics assays
    • Understanding methods of readout needs for assay detection.
    • Ability and enthusiasm for learning new skills and developing new techniques
    • Exceptional communication and data analysis skills, and strong attention to detail
    • Highly motivated, hard-working and curious individual with the ability to think innovatively about difficult research problems
    • Motivates others to do their best; celebrates differences; team-oriented

Preferred Qualifications

    • Experience with using glass, plastic and/or paper as substrates for microfluidic diagnostic devices
    • Experience with programming (LABVIEW, MATLAB, R, Python) with emphasis on coding for systems integration of micro-electronic and micro-electromechanical systems (MEMS) and lab-on-a-chip
    • Basic understanding of molecular biology, genetics, protein biochemistry and nucleic acid biochemistry
    • Well versed in working with analytical chemistry and/or molecular biology teams and understanding translational hurdles of automation and miniaturization of biotechnology


    • Competitive salary
    • Full health/vision/dental benefits
    • Unlimited vacation
    • Free breakfast/lunch/dinner/barista
    • Free gym
    • Public transportation commuter subsidy
    • 401(k) matching