Senior Research Associate - Genome Editing Technology

Mammoth Brisbane, CA
2100 - R&D – R&D /
Full-Time /
Mammoth is currently seeking a talented and detail-oriented Senior Research Associate to join our Editing Technology team. Editing Technology develops next-generation CRISPR tools for therapeutic genome editing applications. The successful candidate will work closely and collaboratively with colleagues to design, execute and analyze genome editing experiments in mammalian cell lines to support the development of new gene editing technologies for human therapeutics. The position requires adaptability, excellent technical and analytical skills, strong organizational and communication skills, as well as the ability to work independently in a fast-paced team-oriented and dynamic environment.


    • Execute molecular cloning, cell culture, transfection and NGS and flow cytometry assays.
    • Provide technical support for phenotyping and analytical characterization of genome editing outcomes
    • Analyze, document and communicate experimental results accurately and in a timely manner. 
    • Conduct all activities in a safe and efficient manner. Adhere to site environmental health and safety (EHS) requirements


    • Bachelor’s degree in molecular and cell biology, immunology, biochemistry, or a related field
    • 5 years relevant laboratory research experience 
    • Knowledge of gene editing systems
    • Proficiency in mammalian cell culture, transfections, molecular cloning, PCR, genomic DNA and NGS library prep


    • Industry work experience 
    • Master’s degree
    • Experience with molecular biology techniques
    • Experience with NGS sample preparation
    • Experience with complex cell culture systems
    • Experience developing human therapies using genome editing systems
    • Knowledge of Microsoft Office Suite and other relevant data analysis software (Flowjo, GraphPad Prism, etc.)
    • Strong organizational and record-keeping skills, excellent interpersonal, verbal and written communication skills.  Highly motivated with strong work ethics
    • Ability to work efficiently and productively in a fast-paced highly collaborative team environment


    • Company-paid health/vision/dental benefits
    • Unlimited vacation and generous sick time
    • Company-sponsored meals and snacks
    • Wellness, caregiver and ergonomics benefits
    • 401(k) with company matching
Base Salary Range: $100,000 - $108,000

The listed base salary range is for Mammoth employees in the Bay Area. Actual base salary will be determined by geographic work location, relevant professional experience, applicable skills, and internal equity. The base salary range for those working remotely outside of the San Francisco Bay Area may differ and will be determined by industry market data for the role and specific region.

Mammoth Biosciences is a biotechnology company focused on leveraging its proprietary ultracompact CRISPR systems to develop long-term curative therapies, as well as other applications such as decentralized precision diagnostics. Founded by CRISPR pioneer and Nobel laureate Jennifer Doudna and Trevor Martin, Janice Chen, and Lucas Harrington, the company’s ultracompact proteins are designed to enable in vivo gene editing in difficult to reach tissues utilizing both nuclease applications and new editing modalities beyond double stranded breaks, including base editing, gene writing, and epigenetic editing. The company is building out its pipeline of potential in vivo gene editing therapeutics and capabilities and has partnerships with leading pharmaceutical and biotechnology companies to broaden the reach of its innovative and proprietary technology. Mammoth’s deep science and industry experience, along with a robust and differentiated intellectual property portfolio, have enabled the company to further its mission to transform the lives of patients and deliver on the full promise of CRISPR technologies.

It is our policy and intent to provide equal opportunity to all persons without regard to race, color, religion, political affiliation, sex/gender (including gender expression/identity, pregnancy, childbirth, and related medical conditions), marital status, registered domestic partner status, sexual orientation, age, ancestry, national origin, veteran status, disability, medical condition, genetic characteristics, and/or any other basis protected by law. This policy covers all facets of employment including, but not limited to: recruitment, selection, placement, promotions, transfers, demotions, terminations, training, and compensation.

Mammoth Biosciences requires that all employees be vaccinated against Covid-19 as a condition of at-will employment, with exceptions for medical or religious reasons in compliance with local, state, and federal law.