IT Manager

Mammoth Brisbane /
General & Admin – G & A /
Mammoth Biosciences, Inc. is harnessing the diversity of nature to power the next-generation of CRISPR products. Through the discovery and development of novel CRISPR systems, the company is enabling the full potential of its platform to read and write the code of life. By leveraging its internal research and development, and exclusive licensing to patents related to Cas12, Cas13, Cas14 and CasPhi, Mammoth Biosciences can provide enhanced diagnostics and genome editing for life science research, healthcare, agriculture, biodefense and more. Mammoth is democratizing disease detection with easy and affordable point-of-care tests that allow real-time and simultaneous detection of multiple conditions, along with high-throughput tests that allow for unprecedented testing volume. Further, the company is transforming disease treatment with its proprietary micro-sized CRISPR proteins that enable new editing and delivery options. Based in Brisbane, CA, Mammoth Biosciences is co-founded by CRISPR pioneer and Nobel Laureate Jennifer Doudna and principal founders Trevor Martin, Janice Chen, and Lucas Harrington. The firm is backed by top institutional investors including Decheng, Mayfield, NFX, and 8VC, and leading individual investors including Brook Byers, Tim Cook, Bob Nelsen, and Jeff Huber. 

Serving as Mammoth’s first in-house IT hire, the IT Manager will be responsible for guiding and executing the company’s IT strategy. This is a full-service role that will require the ability to toggle between tactical and strategic work. The ideal candidate will feel confident being the company’s subject matter expert in IT and bring a whatever-it-takes attitude to managing and scaling the function. This role will come with a great deal of autonomy and report directly to the COO.


    • Manage and prioritize day-to-day IT requests and issues across cloud, on-premise and remote resources
    • Work closely with the HR/Operations teams to onboard and offboard employees while maintaining a high level of confidentiality and discretion
    • Manage IT vendor relationships, including the company’s current contract IT resource, as well as subscriptions and license agreements
    • Execute conference room and individual desktop setup, management and troubleshooting, as needed
    • Advise the leadership team on the development, implementation and improvement of IT policies and best practices for the company 
    • Independently analyze and manage systems upgrades, outages, implementations, integrations and special projects
    • Ensure the security of the company’s IT infrastructure, systems, data and IT assets
    • Serve as the subject matter expert for all IT needs across the organization, partnering closely with both the technical and shared services teams


    • 5 years of experience in (an) IT role(s) that span IT operations, infrastructure, network  and security
    • Experience managing IT as a department of one or few in a startup environment
    • Experience working with AWS
    • Experience with programming languages and operating systems (Windows, MacOS, linux) 
    • Familiarity with cloud computing environments, cloud storage and backups, and serverless technologies 


    • Experience working in a lab-based environment
    • Experience with supporting NetSuite ERP and Salesforce CRM platforms
    • Experience planning, implementing and testing disaster recovery scenarios
    • Experience implementing and/or managing SOX compliance measures
    • Comfort explaining IT needs and training on software and processes to audiences of diverse understanding
    • Hands-on, can-do attitude - no job is too big or too small
    • Ability to work independently and autonomously, and manage up as needed
    • Knowledge of enterprise backups


    • Company-paid health/vision/dental benefits
    • Unlimited vacation and generous sick time
    • Company-sponsored meals and snacks
    • Wellness, caregiver and ergonomics benefits
    • 401(k) with company matching