Research Associate, Pilot Process Development

Watertown, MA /
Pilot Process Development /
Full Time
The Opportunity
This is your opportunity to join a highly driven and ambitious young company that values collaboration, respect, intellectual curiosity, and integrity in our endeavor to transform the way cell therapies are developed and to expand the field of platelet-derived therapeutics.   We have developed a scalable, cGMP-compliant cell culture platform to make engineered human pluripotent stem cell-derived megakaryocytes and platelets.  This is an exciting time to join PBG as we further scale production for human clinical trials and leverage our platform for cell-based drug delivery opportunities. 
 
Who We Are Seeking
The Pilot Process Development team is looking for a Research Associate to join our internal scale-up and development work and support in-house manufacturing. We are looking for a motivated scientist with mammalian cell culture experience and a natural appetite for challenge. Our ideal candidate is a driven, creative thinker, who is a great team player and shares our long‐term vision and passion for leveraging stem cell-derived therapies to cure diseases. Come join our team today and help make a difference in thousands of patients’ lives!

Roles and Responsibilities

    • Maintenance and differentiation of human induced pluripotent stem cells utilizing 2D and 3D platforms
    • Routine culture analysis, including cell counts, flow cytometry, and microscopy
    • Routinely executing milli-fluidic bioreactor runs to generate platelet-like cells (PLCs)
    • Cell and PLC processing, including concentration and cryopreservation
    • Keeping accurate and detailed records of experiments and results
    • Authoring technical documentation such as SOPs and Batch records
    • Organizing an effective working schedule and prioritize tasks appropriately
    • Performing lab maintenance duties, including media preparation, and maintaining stock
    • Presenting results and progress updates to other scientific teams

Preferred Skills and Qualifications

    • Authorized to work in the U.S. – Required
    • BS or MS in Biological Engineering or related field
    • Mammalian cell culture experience – Required
    • Relevant lab experience in academic and/or industry settings – a plus
    • Hands-on experience with flow cytometry, microscopy, milli-fluidic systems, and/or cGMP manufacturing is a plus
    • Ability to work effectively in a dynamic, cross-functional environment, with minimal supervision
    • Excellent attention to detail
    • Ability to work independently and as a part of a team
    • Proven ability to analyze, interpret, and document experimental data
    • Highly motivated, comfortable at multitasking, able to problem solve on the fly
    • Must have scheduling flexibility to enable weekend and holiday work rotations
The Company
PlateletBio, located in Watertown, MA, is a venture-backed biotech startup that was spun out of Harvard Medical School to produce allogeneic cell therapies from engineered induced pluripotent stem cells (iPSCs).