Molecular and Cellular Biology RA

Redwood City, CA /
Partial Reprogramming /
Full-time
The mission of Retro Biosciences is to extend healthy human lifespan by one decade.

We are a well-funded, untraditional bio startup based in Redwood City pursuing multiple programs, including cellular reprogramming therapeutics, with the expertise in cellular reprogramming, automated single-cell -omics, and computational science. We do great science faster than academia and with more flexibility than big pharma. We’re building a team of incredibly accomplished and kind individuals who embrace our culture of rapid iteration, transparency, and versatility.

We are seeking a highly motivated Research Associate in molecular and cellular biology to support the development of our next generation of anti-aging therapies. The candidate will be well-organized, creative, and technically capable of executing multiple molecular and cell biology assays. This position is ideal for an individual who is entrepreneurial and eager to learn and grow exponentially within a collaborative and supportive team of scientists and engineers.

Primary Responsibilities

    • Regular culture of mammalian cells, both primary cells and cell lines
    • Molecular cloning, e. g. design of mammalian DNA constructs,  gene cloning, and functional verifications in cell culture 
    • Transfection of cells and downstream assays, including flow cytometry analysis, DNA and RNA purification, real-time PCR, immunofluorescent staining and imaging
    • Development of new assays, including but not limited to isolation of primary cells from multiple tissues, optimization of culture conditions, bioluminescence detection, FACS, tissue section and staining/imaging
    • Analyze and present experimental data to our internal team and collaborators
    • Maintain an electronic lab notebook and contribute to support documents
    • Regular lab organization and orders

Qualifications

    • B.S or M.S. with 2+ years post-degree research experience
    • Extensive experience with standard molecular and cellular biology techniques, such as mammalian cell culture and transfection, flow cytometry, PCR, immunostaining and imaging
    • Capable of reviewing scientific literature, distill, and communicate information with the science team
    • Working experience with primary tissue is a plus
    • Working knowledge of next generation sequencing, particularly sc-RNA seq, is a plus
    • Highly organized and scientifically rigorous with significant attention to detail
    • Demonstrated ability to work and think independently

You may be a good match for this role if

    • You’re energetic, adaptable, and detail-oriented
    • You’re intellectually curious and deeply pragmatic
    • You communicate openly, clearly, and proactively
    • You can rapidly iterate and improve in a startup environment
    • You have a burning desire to understand aging biology through the lens of modern data-rich measurement technologies