Sr. Associate Scientist
Cambridge, MA
Research – Discovery Biology /
Full-Time /
On-site
Scholar Rock is a biopharmaceutical company that discovers, develops, and delivers life-changing therapies for people with serious diseases that have high unmet need. As a global leader in the biology of the transforming growth factor beta (TGFβ) superfamily of cell proteins and named for the visual resemblance of a scholar rock to protein structures, the clinical-stage company is focused on advancing innovative treatments where protein growth factors are fundamental. Over the past decade, the company has created a pipeline with the potential to advance the standard of care for neuromuscular disease, cardiometabolic disorders, cancer, and other conditions where growth factor-targeted drugs can play a transformational role.
Scholar Rock is the only company to show clinical proof of concept for a muscle-targeted treatment in spinal muscular atrophy (SMA). This commitment to unlocking fundamentally different therapeutic approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. By harnessing cutting-edge science in disease spaces that are historically under-addressed through traditional therapies, Scholar Rock works every day to create new possibilities for patients. Learn more about the company’s approach at ScholarRock.com and follow @ScholarRock and on LinkedIn.
Summary of Position:
At Scholar Rock, our mission is to help patients with serious illnesses through innovative thinking, cutting edge science, and a passion for discovering and developing novel therapeutics. We are seeking a talented and highly motivated Sr. Associate Scientist in molecular biology and metabolism to support our drug discovery programs. This candidate will play an active role in animal model development for pharmacology studies to address biological hypotheses. Working closely with other Research colleagues, this team member will employ molecular and cellular techniques to assess antibody function. This role will play a crucial role in the characterization of potential drugs at the discovery and preclinical stages and thus provides great exposure to the drug discovery process. The successful candidate will be an ambitious and energetic self-starter who is motivated to apply their skills and creativity to drug discovery and enjoys working in a fast-paced team setting.
Position Responsibilities:
- Supervise the execution of pharmacology studies at CROs and perform in-house downstream analysis to support drug discovery program needs.
- Support in vitro studies as needed.
- Maintain detailed records of experimental protocols and data in laboratory notebooks in accordance with company policy.
- Analyze, interpret, and present experimental results to team members and the larger research organization.
- Actively contribute to critical cross-functional team discussions.
Candidate Requirements:
- BA/BS or MS in molecular biology, biochemistry, metabolism, or related field with 2-5 years of experience in drug discovery research.
- Must have experience designing and executing in vivo animal models of metabolic disease. Experience with pharmacology studies is a plus.
- Experience with molecular biology techniques such as DNA and RNA extraction, qPCR, protein quantification, ELISA, and enzymatic assays is required. Experience with mammalian cell culture is desired.
- Demonstrated ability to work independently, including experimental design and execution, in a fast-paced team-oriented environment.
- Strong organizational skills and attention to detail and ability to troubleshoot problems and propose creative solutions.
- Ability to effectively communicate and document research.
- Self-motivated and comfortable operating independently and within teams.
Scholar Rock is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.
