Laboratory Technologist

Durham, NC
Laboratory Operations /
Full-Time /
Xilis, Inc. is an innovation-driven biotech company developing its proprietary MicroOrganoSphere (“MOS”) Technology for functional precision oncology. Xilis’ MOS Technology enables rapid and scalable generation of patient tumor models that retain patient-specific tumor biology and tumor microenvironment, representing one of the most translationally-relevant ex vivo technologies for precision oncology drug discovery and development. Located in Research Triangle Park, Durham, NC, Xilis is building a functional precision medicine platform that incorporates scaled multi-modal profiling of therapeutic activity and AI/ML-enabled analytics to catalyze functional precision medicine drug discovery, development and diagnostics. Collectively, Xilis aims to harness its MOS Platform to enable development of the most effective therapeutics and guide them to the right patients at the right time.

*The schedule for this position is Full-Time, Tuesday-Saturday*
The candidate will perform quality control and environmental monitoring testing procedures in accordance with SOPs and appropriate regulatory guidelines and help to improve and streamline those processes. This will include performing end-to-end laboratory processes such as PCR/qPCR, nucleic acid extraction, cell-based microscopy and imaging, and operation of critical laboratory equipment. The successful candidate will bring exceptional skills and abilities to the laboratory. He or she will also have strong attention to detail and the integrity to precisely report any deviation or issue observed in the laboratory. The candidate will report to Xilis’ Head of Laboratory Operations.


    • Participate in all phases of biological sample testing procedures for the Quality Control team
    • Perform routine equipment maintenance and cleaning
    • Assist with the improvement of Standard Operating Procedures (SOPs)Identify and document potential QC or processing issues and report to management
    • Operate successfully in a rapidly changing, fast-paced, mission-driven environment
    • Share thoughts and ideas on how to improve performance in the lab
    • Perform support tasks across the company as needs arise


    • A.S. or B.S. degree in biology, molecular biology, biomedical engineering, biotechnology, or equivalent
    • 2+ years of experience in a laboratory environment, preferably in an industry setting
    • Hands-on laboratory experience including PCR/qPCR, nucleic acid extraction, and pipetting
    • Experience with mammalian cell culture is strongly preferred
    • Experience working cross-functionally, demonstrated exceptional written and verbal communication
    • A strong sense of commitment, integrity, and handling challenges collaborativelyExperience and interest in a high-growth startup is preferred
Xilis was created when its three founders — an engineer, a physician, and a biologist — decided to come together and commercialize their technology to transform cancer care. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. We do not discriminate on the basis of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, or Veteran status. Furthermore, even if your work experience isn't perfectly aligned with what we've described above, if you're excited about what we're building then we want to talk to you!
Xilis offers comprehensive health, vision, dental & retirement plans, and unlimited PTO. We are a remote-friendly team: our headquarters are in Durham, North Carolina, but we have team members across the US (and beyond!).