Senior Manager, Cost Accounting

Durham, NC (Capitola) /
Finance / Accounting /
Xilis, Inc is a Duke spinoff founded by Duke professors David Hsu (M.D./Ph.D) and Xiling Shen (Ph.D) in Durham, North Carolina. The company has been developing cutting-edge Patient-Derived Micro-Organospheres (PDMO) technology for precision cancer diagnostics and drug development. Xilis’ transformative platform recreates patient-specific tumors in their 3D and environmental complexity at micro-scale ex vivo, allowing ultra-high-throughput, clinically relevant, and affordable experimental selection of the safest, most effective drugs for each and every patient in a matter of days. The company is funded by Silicon Valley and New York venture firms that are leaders in the healthcare space and have invested in top precision medicine companies including Foundation Medicine and Guardant Health.

We are looking for a highly motivated individual to join us as a Senior Manager, Cost Accounting.  This newly created role will have overall responsibility for ensuring our inventory, cost of sales, and other related items are fairly stated in accordance with GAAP. The ideal candidate will have experience working with ERP systems, preferably with a diagnostic company, and can complete tasks and projects quickly with little guidance in solving problems that affect people within the team and other related groups.

The Senior Manager, Cost Accounting will report to the VP Finance, and will build out and manage the cost accounting function and inventory processes while at the same time participating in the project team for the ERP system implementation.  This position will also be responsible for managing the financial forecasting for revenue and costing working closely with other teams within the organization.
The professional will oversee the inventory and cost accounting systems and related reporting, including variance analysis and financial forecast updates; will frequently interact with the Company’s R&D team and is expected to voice thoughtful opinions on cost accounting and system best practices.


    • Maintain and improve current cost accounting process for month-end close
    • Develop costing and inventory tracking process/system until ERP system is in place
    • Take a lead role in the design and implementation of the Company’s ERP system including inventory, costing, and procurement
    • Develop and provide management with key performance indicators for decision-making purposes as the company grows
    • Review all revenue contracts and participate in project team meetings that impact revenue and cost
    • Assist manufacturing, quality, and supply chain departments by participating in project teams as needed
    • Work with accounting team as needed on additional month-end projects
    • Support the business development team as needed


    • Bachelor’s Degree in Finance, Accounting, or Business Administration
    • Minimum of 10 years of relevant cost accounting leadership experience in a manufacturing environment, preferably diagnostics/biotech
    • Experience with standard costing systems and implementation of standard costing systems
    • Advanced Excel knowledge
    • Highly organized, proactive, and collaborative
    • Willingness to take on significant responsibility
    • Ability to work in a fast-paced, deadline-driven environment
    • Ability to think critically and analytically
    • Proficiency with an ERP System and implementations
    • CPA preferred but not required
Xilis was created when its three founders — an engineer, a physician, and a biologist — decided to come together and commercialize their technology to transform cancer care. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. We do not discriminate on the basis of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, or Veteran status. Furthermore, even if your work experience isn't perfectly aligned with what we've described above, if you're excited about what we're building then we want to talk to you!

Xilis offers comprehensive health, vision, dental & retirement plans, and unlimited PTO. We are a remote-friendly team: our headquarters are in Durham, North Carolina, but we have team members across the US (and beyond!).